Hydrolase activity

Hydrolase activity

• ABCA3: ATP-binding cassette, sub-family A (ABC1), member 3
• ABCB11: ATP-binding cassette, sub-family B (MDR/TAP), member 11
• ABCB4: ATP-binding cassette, sub-family B (MDR/TAP), member 4
• ABCB7: ATP-binding cassette, sub-family B (MDR/TAP), member 7
• ABCD1: ATP-binding cassette, sub-family D (ALD), member 1
• ABCG5: ATP-binding cassette, sub-family G (WHITE), member 5
• ABCG8: ATP-binding cassette, sub-family G (WHITE), member 8
• ADA: adenosine deaminase
• ADAMTS13: ADAM metallopeptidase with thrombospondin type 1 motif, 13
• ADAMTS2: ADAM metallopeptidase with thrombospondin type 1 motif, 2
• AGA: aspartylglucosaminidase
• AGL: amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase
• AHCY: adenosylhomocysteinase
• ALPL: alkaline phosphatase, liver/bone/kidney
• ANG: angiogenin, ribonuclease, RNase A family, 5
• APTX: aprataxin
• ARG1: arginase 1
• ARSA: arylsulfatase A
• ARSB: arylsulfatase B
• ARSE: arylsulfatase E (chondrodysplasia punctata 1)
• ASAH1: N-acylsphingosine amidohydrolase (acid ceramidase) 1
• ASPA: aspartoacylase
• ATL1: atlastin GTPase 1
• ATP1A2: ATPase, Na+/K+ transporting, alpha 2 polypeptide
• ATP1A3: ATPase, Na+/K+ transporting, alpha 3 polypeptide
• ATP2A1: ATPase, Ca++ transporting, cardiac muscle, fast twitch 1
• ATP2A2: ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
• ATP2B2: ATPase, Ca++ transporting, plasma membrane 2
• ATP7A: ATPase, Cu++ transporting, alpha polypeptide
• ATP7B: ATPase, Cu++ transporting, beta polypeptide
• ATP8B1: ATPase, aminophospholipid transporter, class I, type 8B, member 1
• ATRX: alpha thalassemia/mental retardation syndrome X-linked
• ATXN3: ataxin 3
• BCHE: butyrylcholinesterase
• BLM: Bloom syndrome, RecQ helicase-like
• BRIP1: BRCA1 interacting protein C-terminal helicase 1
• C10orf2: chromosome 10 open reading frame 2
• CAPN3: calpain 3, (p94)
• CASR: calcium-sensing receptor
• CFTR: cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
• CTDP1: CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
• CTSA: cathepsin A
• CYLD: cylindromatosis (turban tumor syndrome)
• DICER1: dicer 1, ribonuclease type III
• DNAH5: dynein, axonemal, heavy chain 5
• DNM2: dynamin 2
• DYNC1H1: dynein, cytoplasmic 1, heavy chain 1
• ELANE: elastase, neutrophil expressed
• EPM2A: epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)
• ERAP1: endoplasmic reticulum aminopeptidase 1
• ERCC2: excision repair cross-complementing rodent repair deficiency, complementation group 2
• ERCC3: excision repair cross-complementing rodent repair deficiency, complementation group 3
• ERCC6: excision repair cross-complementing rodent repair deficiency, complementation group 6
• EYA1: eyes absent homolog 1 (Drosophila)
• F12: coagulation factor XII (Hageman factor)
• F2: coagulation factor II (thrombin)
• FAH: fumarylacetoacetate hydrolase (fumarylacetoacetase)
• FIG4: FIG4 homolog, SAC1 lipid phosphatase domain containing (S. cerevisiae)
• FUCA1: fucosidase, alpha-L- 1, tissue
• G6PC: glucose-6-phosphatase, catalytic subunit
• GAA: glucosidase, alpha; acid
• GALNS: galactosamine (N-acetyl)-6-sulfate sulfatase
• GBA: glucosidase, beta, acid
• GCH1: GTP cyclohydrolase 1
• GLA: galactosidase, alpha
• GLB1: galactosidase, beta 1
• GNAI3: guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3
• GNAS: GNAS complex locus
• GNAT2: guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2
• GNPAT: glyceronephosphate O-acyltransferase
• GNS: glucosamine (N-acetyl)-6-sulfatase
• GUSB: glucuronidase, beta
• HPSE2: heparanase 2
• HTRA1: HtrA serine peptidase 1
• IDS: iduronate 2-sulfatase
• IGHMBP2: immunoglobulin mu binding protein 2
• KIF1B: kinesin family member 1B
• KL: klotho
• LCT: lactase
• LIPA: lipase A, lysosomal acid, cholesterol esterase
• LIPH: lipase, member H
• LPIN2: lipin 2
• LPL: lipoprotein lipase
• LRRK2: leucine-rich repeat kinase 2
• MCM6: minichromosome maintenance complex component 6
• MLH1: mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli)
• MSH2: mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli)
• MSH6: mutS homolog 6 (E. coli)
• MT-ATP6: mitochondrially encoded ATP synthase 6
• MTM1: myotubularin 1
• MTMR2: myotubularin related protein 2
• MYH3: myosin, heavy chain 3, skeletal muscle, embryonic
• MYH7: myosin, heavy chain 7, cardiac muscle, beta
• MYH9: myosin, heavy chain 9, non-muscle
• MYO6: myosin VI
• MYO7A: myosin VIIA
• NAGA: N-acetylgalactosaminidase, alpha-
• NBN: nibrin
• NCF1: neutrophil cytosolic factor 1
• NEU1: sialidase 1 (lysosomal sialidase)
• OCRL: oculocerebrorenal syndrome of Lowe
• OPA1: optic atrophy 1 (autosomal dominant)
• PARK7: parkinson protein 7
• PCSK9: proprotein convertase subtilisin/kexin type 9
• PDP1: pyruvate dehydrogenase phosphatase catalytic subunit 1
• PEPD: peptidase D
• PEX1: peroxisomal biogenesis factor 1
• PLA2G6: phospholipase A2, group VI (cytosolic, calcium-independent)
• PLCB4: phospholipase C, beta 4
• PLG: plasminogen
• PMS2: PMS2 postmeiotic segregation increased 2 (S. cerevisiae)
• PNPLA2: patatin-like phospholipase domain containing 2
• PPT1: palmitoyl-protein thioesterase 1
• PROC: protein C (inactivator of coagulation factors Va and VIIIa)
• PRSS1: protease, serine, 1 (trypsin 1)
• PSEN1: presenilin 1
• PSEN2: presenilin 2 (Alzheimer disease 4)
• PTEN: phosphatase and tensin homolog
• PTPN11: protein tyrosine phosphatase, non-receptor type 11
• PTPN22: protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
• RAB23: RAB23, member RAS oncogene family
• RAB7A: RAB7A, member RAS oncogene family
• RAD50: RAD50 homolog (S. cerevisiae)
• RAD51: RAD51 homolog (S. cerevisiae)
• RECQL4: RecQ protein-like 4
• REN: renin
• RNASEH2A: ribonuclease H2, subunit A
• SALL1: sal-like 1 (Drosophila)
• SAR1B: SAR1 homolog B (S. cerevisiae)
• SEPT9: septin 9
• SETX: senataxin
• SI: sucrase-isomaltase (alpha-glucosidase)
• SMARCA4: SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
• SMARCAL1: SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1
• SMC1A: structural maintenance of chromosomes 1A
• SMC3: structural maintenance of chromosomes 3
• SPAST: spastin
• SPG7: spastic paraplegia 7 (pure and complicated autosomal recessive)
• TMPRSS3: transmembrane protease, serine 3
• TNNT2: troponin T type 2 (cardiac)
• TOR1A: torsin family 1, member A (torsin A)
• TREX1: three prime repair exonuclease 1
• UCHL1: ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
• USP9Y: ubiquitin specific peptidase 9, Y-linked
• VCP: valosin containing protein
• WRN: Werner syndrome, RecQ helicase-like

Source: Gene Ontology Consortium.