Negative regulation of metabolic process
- ACADVL: acyl-CoA dehydrogenase, very long chain
- ACVRL1: activin A receptor type II-like 1
- AKT1: v-akt murine thymoma viral oncogene homolog 1
- APC: adenomatous polyposis coli
- APOE: apolipoprotein E
- AR: androgen receptor
- ATN1: atrophin 1
- ATP8B1: ATPase, aminophospholipid transporter, class I, type 8B, member 1
- ATXN1: ataxin 1
- ATXN2: ataxin 2
- BARD1: BRCA1 associated RING domain 1
- BCOR: BCL6 corepressor
- BLM: Bloom syndrome, RecQ helicase-like
- BMPR2: bone morphogenetic protein receptor, type II (serine/threonine kinase)
- BRCA1: breast cancer 1, early onset
- BSCL2: Berardinelli-Seip congenital lipodystrophy 2 (seipin)
- CAPN3: calpain 3, (p94)
- CAV3: caveolin 3
- CDAN1: codanin 1
- CDC73: cell division cycle 73
- CDKN1C: cyclin-dependent kinase inhibitor 1C (p57, Kip2)
- CLN3: ceroid-lipofuscinosis, neuronal 3
- CREBBP: CREB binding protein
- CST3: cystatin C
- CTNNB1: catenin (cadherin-associated protein), beta 1, 88kDa
- DICER1: dicer 1, ribonuclease type III
- DMD: dystrophin
- DNMT1: DNA (cytosine-5-)-methyltransferase 1
- DRD3: dopamine receptor D3
- EDNRB: endothelin receptor type B
- EHMT1: euchromatic histone-lysine N-methyltransferase 1
- EIF2B3: eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa
- EIF2B4: eukaryotic translation initiation factor 2B, subunit 4 delta, 67kDa
- EIF2B5: eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa
- ELANE: elastase, neutrophil expressed
- ENG: endoglin
- EP300: E1A binding protein p300
- F2: coagulation factor II (thrombin)
- FGFR2: fibroblast growth factor receptor 2
- FLCN: folliculin
- FLNA: filamin A, alpha
- FMR1: fragile X mental retardation 1
- FOXC2: forkhead box C2 (MFH-1, mesenchyme forkhead 1)
- FOXG1: forkhead box G1
- FOXL2: forkhead box L2
- FOXP3: forkhead box P3
- G6PD: glucose-6-phosphate dehydrogenase
- GBA: glucosidase, beta, acid
- GLA: galactosidase, alpha
- GLI3: GLI family zinc finger 3
- GNAI3: guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3
- HRAS: v-Ha-ras Harvey rat sarcoma viral oncogene homolog
- HSPB1: heat shock 27kDa protein 1
- INS: insulin
- ITM2B: integral membrane protein 2B
- KAT6B: K(lysine) acetyltransferase 6B
- KMT2D: myeloid/lymphoid or mixed-lineage leukemia 2
- LIMK1: LIM domain kinase 1
- LRP5: low density lipoprotein receptor-related protein 5
- MECP2: methyl CpG binding protein 2 (Rett syndrome)
- MEN1: multiple endocrine neoplasia I
- MSH2: mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli)
- MSH6: mutS homolog 6 (E. coli)
- MSX2: msh homeobox 2
- MTMR2: myotubularin related protein 2
- NF1: neurofibromin 1
- NF2: neurofibromin 2 (merlin)
- NIPBL: Nipped-B homolog (Drosophila)
- NLRP12: NLR family, pyrin domain containing 12
- NOG: noggin
- NR0B1: nuclear receptor subfamily 0, group B, member 1
- NSD1: nuclear receptor binding SET domain protein 1
- PARK2: parkinson protein 2, E3 ubiquitin protein ligase (parkin)
- PAX2: paired box 2
- PCSK9: proprotein convertase subtilisin/kexin type 9
- PDGFB: platelet-derived growth factor beta polypeptide
- PITX2: paired-like homeodomain 2
- PML: promyelocytic leukemia
- PRICKLE1: prickle homolog 1 (Drosophila)
- PRKAG2: protein kinase, AMP-activated, gamma 2 non-catalytic subunit
- PRNP: prion protein
- PTCH1: patched 1
- PTEN: phosphatase and tensin homolog
- RARA: retinoic acid receptor, alpha
- RB1: retinoblastoma 1
- RPS19: ribosomal protein S19
- RPS26: ribosomal protein S26
- RUNX2: runt-related transcription factor 2
- SALL1: sal-like 1 (Drosophila)
- SERPING1: serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
- SHH: sonic hedgehog
- SKI: v-ski sarcoma viral oncogene homolog (avian)
- SMAD3: SMAD family member 3
- SMAD4: SMAD family member 4
- SMARCA4: SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
- SMARCE1: SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1
- SMC1A: structural maintenance of chromosomes 1A
- SMC3: structural maintenance of chromosomes 3
- SMPD1: sphingomyelin phosphodiesterase 1, acid lysosomal
- SNAI2: snail homolog 2 (Drosophila)
- SNCA: synuclein, alpha (non A4 component of amyloid precursor)
- SOD1: superoxide dismutase 1, soluble
- SOX2: SRY (sex determining region Y)-box 2
- SOX9: SRY (sex determining region Y)-box 9
- SPRED1: sprouty-related, EVH1 domain containing 1
- STAT3: signal transducer and activator of transcription 3 (acute-phase response factor)
- T: T, brachyury homolog (mouse)
- TARDBP: TAR DNA binding protein
- TFAP2A: transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
- TFAP2B: transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
- TGFB1: transforming growth factor, beta 1
- TGIF1: TGFB-induced factor homeobox 1
- TINF2: TERF1 (TRF1)-interacting nuclear factor 2
- TP53: tumor protein p53
- TP63: tumor protein p63
- TRPS1: trichorhinophalangeal syndrome I
- TSC1: tuberous sclerosis 1
- TSC2: tuberous sclerosis 2
- TWIST1: twist basic helix-loop-helix transcription factor 1
- UCHL1: ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
- UGT1A1: UDP glucuronosyltransferase 1 family, polypeptide A1
- VHL: von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase
- VLDLR: very low density lipoprotein receptor
- WNT4: wingless-type MMTV integration site family, member 4
- WT1: Wilms tumor 1
- ZIC2: Zic family member 2
Source: Gene Ontology Consortium
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