Negative regulation of cellular process
- ABCA1: ATP-binding cassette, sub-family A (ABC1), member 1
- ACADVL: acyl-CoA dehydrogenase, very long chain
- ACVR1: activin A receptor, type I
- ACVRL1: activin A receptor type II-like 1
- ADA: adenosine deaminase
- ADAMTSL2: ADAMTS-like 2
- AKT1: v-akt murine thymoma viral oncogene homolog 1
- ANG: angiogenin, ribonuclease, RNase A family, 5
- APC: adenomatous polyposis coli
- APOA1: apolipoprotein A-I
- APOE: apolipoprotein E
- AR: androgen receptor
- ATM: ataxia telangiectasia mutated
- ATN1: atrophin 1
- ATP8B1: ATPase, aminophospholipid transporter, class I, type 8B, member 1
- ATXN1: ataxin 1
- ATXN2: ataxin 2
- AVP: arginine vasopressin
- BARD1: BRCA1 associated RING domain 1
- BCOR: BCL6 corepressor
- BLM: Bloom syndrome, RecQ helicase-like
- BMPR2: bone morphogenetic protein receptor, type II (serine/threonine kinase)
- BRAF: v-raf murine sarcoma viral oncogene homolog B1
- BRCA1: breast cancer 1, early onset
- BRCA2: breast cancer 2, early onset
- BRIP1: BRCA1 interacting protein C-terminal helicase 1
- CAPN3: calpain 3, (p94)
- CAV3: caveolin 3
- CD40LG: CD40 ligand
- CDAN1: codanin 1
- CDC73: cell division cycle 73
- CDH1: cadherin 1, type 1, E-cadherin (epithelial)
- CDKN1C: cyclin-dependent kinase inhibitor 1C (p57, Kip2)
- CHEK2: checkpoint kinase 2
- CLCF1: cardiotrophin-like cytokine factor 1
- CLN3: ceroid-lipofuscinosis, neuronal 3
- COL18A1: collagen, type XVIII, alpha 1
- COL4A3: collagen, type IV, alpha 3 (Goodpasture antigen)
- COMP: cartilage oligomeric matrix protein
- CREBBP: CREB binding protein
- CRLF1: cytokine receptor-like factor 1
- CST3: cystatin C
- CTNNB1: catenin (cadherin-associated protein), beta 1, 88kDa
- CYLD: cylindromatosis (turban tumor syndrome)
- DFNA5: deafness, autosomal dominant 5
- DICER1: dicer 1, ribonuclease type III
- DMD: dystrophin
- DNMT1: DNA (cytosine-5-)-methyltransferase 1
- DRD3: dopamine receptor D3
- EDNRB: endothelin receptor type B
- EHMT1: euchromatic histone-lysine N-methyltransferase 1
- EIF2B3: eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa
- EIF2B4: eukaryotic translation initiation factor 2B, subunit 4 delta, 67kDa
- EIF2B5: eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa
- ELANE: elastase, neutrophil expressed
- EMD: emerin
- ENG: endoglin
- EP300: E1A binding protein p300
- ERCC2: excision repair cross-complementing rodent repair deficiency, complementation group 2
- ERCC3: excision repair cross-complementing rodent repair deficiency, complementation group 3
- F2: coagulation factor II (thrombin)
- FANCG: Fanconi anemia, complementation group G
- FBN1: fibrillin 1
- FBN2: fibrillin 2
- FGF23: fibroblast growth factor 23
- FGFR2: fibroblast growth factor receptor 2
- FKTN: fukutin
- FLCN: folliculin
- FLT4: fms-related tyrosine kinase 4
- FMR1: fragile X mental retardation 1
- FOXC1: forkhead box C1
- FOXC2: forkhead box C2 (MFH-1, mesenchyme forkhead 1)
- FOXG1: forkhead box G1
- FOXL2: forkhead box L2
- FOXP3: forkhead box P3
- FXN: frataxin
- FZD4: frizzled family receptor 4
- G6PD: glucose-6-phosphate dehydrogenase
- GATA1: GATA binding protein 1 (globin transcription factor 1)
- GBA: glucosidase, beta, acid
- GLA: galactosidase, alpha
- GLI3: GLI family zinc finger 3
- GLRA1: glycine receptor, alpha 1
- GNAI3: guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3
- GPR98: G protein-coupled receptor 98
- GSN: gelsolin
- HRAS: v-Ha-ras Harvey rat sarcoma viral oncogene homolog
- HSPB1: heat shock 27kDa protein 1
- HTT: huntingtin
- IL1A: interleukin 1, alpha
- INS: insulin
- IRF6: interferon regulatory factor 6
- ITGA6: integrin, alpha 6
- ITM2B: integral membrane protein 2B
- JAG1: jagged 1
- JAK2: Janus kinase 2
- KAT6B: K(lysine) acetyltransferase 6B
- KCNJ11: potassium inwardly-rectifying channel, subfamily J, member 11
- KIT: v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
- KMT2D: myeloid/lymphoid or mixed-lineage leukemia 2
- KRIT1: KRIT1, ankyrin repeat containing
- LEPRE1: leucine proline-enriched proteoglycan (leprecan) 1
- LIMK1: LIM domain kinase 1
- LRP5: low density lipoprotein receptor-related protein 5
- LRRK2: leucine-rich repeat kinase 2
- MAP2K1: mitogen-activated protein kinase kinase 1
- MCM6: minichromosome maintenance complex component 6
- MECP2: methyl CpG binding protein 2 (Rett syndrome)
- MED12: mediator complex subunit 12
- MEN1: multiple endocrine neoplasia I
- MFN2: mitofusin 2
- MSH2: mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli)
- MSH6: mutS homolog 6 (E. coli)
- MSX1: msh homeobox 1
- MSX2: msh homeobox 2
- MTMR2: myotubularin related protein 2
- NBN: nibrin
- NDRG1: N-myc downstream regulated 1
- NF1: neurofibromin 1
- NF2: neurofibromin 2 (merlin)
- NGF: nerve growth factor (beta polypeptide)
- NIPBL: Nipped-B homolog (Drosophila)
- NLRP12: NLR family, pyrin domain containing 12
- NLRP3: NLR family, pyrin domain containing 3
- NOD2: nucleotide-binding oligomerization domain containing 2
- NOG: noggin
- NOTCH2: notch 2
- NR0B1: nuclear receptor subfamily 0, group B, member 1
- NSD1: nuclear receptor binding SET domain protein 1
- NTRK1: neurotrophic tyrosine kinase, receptor, type 1
- OPA1: optic atrophy 1 (autosomal dominant)
- PARK2: parkinson protein 2, E3 ubiquitin protein ligase (parkin)
- PARK7: parkinson protein 7
- PAX2: paired box 2
- PAX6: paired box 6
- PAX8: paired box 8
- PCSK9: proprotein convertase subtilisin/kexin type 9
- PDCD10: programmed cell death 10
- PDGFB: platelet-derived growth factor beta polypeptide
- PDGFRA: platelet-derived growth factor receptor, alpha polypeptide
- PITX2: paired-like homeodomain 2
- PKD1: polycystic kidney disease 1 (autosomal dominant)
- PKD2: polycystic kidney disease 2 (autosomal dominant)
- PKHD1: polycystic kidney and hepatic disease 1 (autosomal recessive)
- PKP2: plakophilin 2
- PLAGL1: pleiomorphic adenoma gene-like 1
- PLG: plasminogen
- PML: promyelocytic leukemia
- POU3F4: POU class 3 homeobox 4
- PPT1: palmitoyl-protein thioesterase 1
- PRICKLE1: prickle homolog 1 (Drosophila)
- PRKAG2: protein kinase, AMP-activated, gamma 2 non-catalytic subunit
- PRNP: prion protein
- PROC: protein C (inactivator of coagulation factors Va and VIIIa)
- PROK2: prokineticin 2
- PSEN1: presenilin 1
- PTCH1: patched 1
- PTEN: phosphatase and tensin homolog
- PTPN22: protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
- RAB7A: RAB7A, member RAS oncogene family
- RAF1: v-raf-1 murine leukemia viral oncogene homolog 1
- RARA: retinoic acid receptor, alpha
- RASA1: RAS p21 protein activator (GTPase activating protein) 1
- RB1: retinoblastoma 1
- ROR2: receptor tyrosine kinase-like orphan receptor 2
- RPS26: ribosomal protein S26
- RPS6KA3: ribosomal protein S6 kinase, 90kDa, polypeptide 3
- RUNX2: runt-related transcription factor 2
- SACS: spastic ataxia of Charlevoix-Saguenay (sacsin)
- SALL1: sal-like 1 (Drosophila)
- SBDS: Shwachman-Bodian-Diamond syndrome
- SHANK3: SH3 and multiple ankyrin repeat domains 3
- SHH: sonic hedgehog
- SIX1: SIX homeobox 1
- SKI: v-ski sarcoma viral oncogene homolog (avian)
- SLC25A4: solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4
- SMAD3: SMAD family member 3
- SMAD4: SMAD family member 4
- SMARCA4: SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
- SMARCB1: SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1
- SMARCE1: SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1
- SMC1A: structural maintenance of chromosomes 1A
- SMC3: structural maintenance of chromosomes 3
- SMPD1: sphingomyelin phosphodiesterase 1, acid lysosomal
- SNAI2: snail homolog 2 (Drosophila)
- SNCA: synuclein, alpha (non A4 component of amyloid precursor)
- SOD1: superoxide dismutase 1, soluble
- SOST: sclerostin
- SOX2: SRY (sex determining region Y)-box 2
- SOX9: SRY (sex determining region Y)-box 9
- SPRED1: sprouty-related, EVH1 domain containing 1
- SQSTM1: sequestosome 1
- STAT3: signal transducer and activator of transcription 3 (acute-phase response factor)
- STK11: serine/threonine kinase 11
- T: T, brachyury homolog (mouse)
- TARDBP: TAR DNA binding protein
- TBX1: T-box 1
- TBX5: T-box 5
- TEK: TEK tyrosine kinase, endothelial
- TERT: telomerase reverse transcriptase
- TFAP2A: transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
- TFAP2B: transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
- TGFB1: transforming growth factor, beta 1
- TGFBI: transforming growth factor, beta-induced, 68kDa
- TGFBR1: transforming growth factor, beta receptor 1
- TGFBR2: transforming growth factor, beta receptor II (70/80kDa)
- TGIF1: TGFB-induced factor homeobox 1
- TINF2: TERF1 (TRF1)-interacting nuclear factor 2
- TMEM127: transmembrane protein 127
- TP53: tumor protein p53
- TP63: tumor protein p63
- TRIOBP: TRIO and F-actin binding protein
- TRPS1: trichorhinophalangeal syndrome I
- TRPV4: transient receptor potential cation channel, subfamily V, member 4
- TSC1: tuberous sclerosis 1
- TSC2: tuberous sclerosis 2
- TWIST1: twist basic helix-loop-helix transcription factor 1
- UCHL1: ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
- UMOD: uromodulin
- USH2A: Usher syndrome 2A (autosomal recessive, mild)
- VHL: von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase
- VLDLR: very low density lipoprotein receptor
- WFS1: Wolfram syndrome 1 (wolframin)
- WNT4: wingless-type MMTV integration site family, member 4
- WT1: Wilms tumor 1
- XIAP: X-linked inhibitor of apoptosis
- XPC: xeroderma pigmentosum, complementation group C
- ZIC2: Zic family member 2
Source: Gene Ontology Consortium
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