Regulation of signaling
- ABCA1: ATP-binding cassette, sub-family A (ABC1), member 1
- ABCC8: ATP-binding cassette, sub-family C (CFTR/MRP), member 8
- ACVR1: activin A receptor, type I
- ACVRL1: activin A receptor type II-like 1
- ADA: adenosine deaminase
- ADAMTSL2: ADAMTS-like 2
- AGPAT2: 1-acylglycerol-3-phosphate O-acyltransferase 2
- AKT1: v-akt murine thymoma viral oncogene homolog 1
- ALK: anaplastic lymphoma receptor tyrosine kinase
- ALS2: amyotrophic lateral sclerosis 2 (juvenile)
- APC: adenomatous polyposis coli
- APOA1: apolipoprotein A-I
- APOE: apolipoprotein E
- APP: amyloid beta (A4) precursor protein
- ARFGEF2: ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)
- ATM: ataxia telangiectasia mutated
- AVP: arginine vasopressin
- BMPR1A: bone morphogenetic protein receptor, type IA
- BMPR2: bone morphogenetic protein receptor, type II (serine/threonine kinase)
- BRAF: v-raf murine sarcoma viral oncogene homolog B1
- C3: complement component 3
- CACNA1A: calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
- CACNA1C: calcium channel, voltage-dependent, L type, alpha 1C subunit
- CAPN3: calpain 3, (p94)
- CARD14: caspase recruitment domain family, member 14
- CAV3: caveolin 3
- CDC73: cell division cycle 73
- CDKL5: cyclin-dependent kinase-like 5
- CDKN1C: cyclin-dependent kinase inhibitor 1C (p57, Kip2)
- CHD7: chromodomain helicase DNA binding protein 7
- CHN1: chimerin 1
- CHRNA4: cholinergic receptor, nicotinic, alpha 4 (neuronal)
- CHRNB2: cholinergic receptor, nicotinic, beta 2 (neuronal)
- CLCF1: cardiotrophin-like cytokine factor 1
- COL1A1: collagen, type I, alpha 1
- CREBBP: CREB binding protein
- CRLF1: cytokine receptor-like factor 1
- CSF1R: colony stimulating factor 1 receptor
- CTNNB1: catenin (cadherin-associated protein), beta 1, 88kDa
- CYLD: cylindromatosis (turban tumor syndrome)
- DRD3: dopamine receptor D3
- EDN3: endothelin 3
- ELANE: elastase, neutrophil expressed
- EMD: emerin
- ENG: endoglin
- EP300: E1A binding protein p300
- ERBB2: v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)
- EVC: Ellis van Creveld syndrome
- F2: coagulation factor II (thrombin)
- FBN1: fibrillin 1
- FBN2: fibrillin 2
- FGD1: FYVE, RhoGEF and PH domain containing 1
- FGD4: FYVE, RhoGEF and PH domain containing 4
- FGF23: fibroblast growth factor 23
- FGFR1: fibroblast growth factor receptor 1
- FGFR2: fibroblast growth factor receptor 2
- FGFR3: fibroblast growth factor receptor 3
- FGFR4: fibroblast growth factor receptor 4
- FKTN: fukutin
- FLCN: folliculin
- FLNA: filamin A, alpha
- FLT4: fms-related tyrosine kinase 4
- FXN: frataxin
- FZD4: frizzled family receptor 4
- GBA: glucosidase, beta, acid
- GDF6: growth differentiation factor 6
- GH1: growth hormone 1
- GHRHR: growth hormone releasing hormone receptor
- GJA1: gap junction protein, alpha 1, 43kDa
- GLI3: GLI family zinc finger 3
- GLRA1: glycine receptor, alpha 1
- GNAS: GNAS complex locus
- GPR143: G protein-coupled receptor 143
- HAX1: HCLS1 associated protein X-1
- HRAS: v-Ha-ras Harvey rat sarcoma viral oncogene homolog
- HSPB1: heat shock 27kDa protein 1
- HTT: huntingtin
- IGF2: insulin-like growth factor 2 (somatomedin A)
- IKBKG: inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
- IL23R: interleukin 23 receptor
- INS: insulin
- JAK2: Janus kinase 2
- KCNJ11: potassium inwardly-rectifying channel, subfamily J, member 11
- KIT: v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
- KRAS: v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog
- LDLRAP1: low density lipoprotein receptor adaptor protein 1
- LGI1: leucine-rich, glioma inactivated 1
- LHCGR: luteinizing hormone/choriogonadotropin receptor
- LITAF: lipopolysaccharide-induced TNF factor
- LRP5: low density lipoprotein receptor-related protein 5
- LRRK2: leucine-rich repeat kinase 2
- MAP2K1: mitogen-activated protein kinase kinase 1
- MAP2K2: mitogen-activated protein kinase kinase 2
- MC1R: melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
- MED12: mediator complex subunit 12
- MEN1: multiple endocrine neoplasia I
- MFN2: mitofusin 2
- MID1: midline 1 (Opitz/BBB syndrome)
- MLL2: myeloid/lymphoid or mixed-lineage leukemia 2
- MSX1: msh homeobox 1
- NF1: neurofibromin 1
- NF2: neurofibromin 2 (merlin)
- NGF: nerve growth factor (beta polypeptide)
- NLRP12: NLR family, pyrin domain containing 12
- NLRP3: NLR family, pyrin domain containing 3
- NOD2: nucleotide-binding oligomerization domain containing 2
- NOG: noggin
- NOTCH2: notch 2
- NR0B1: nuclear receptor subfamily 0, group B, member 1
- NRAS: neuroblastoma RAS viral (v-ras) oncogene homolog
- NTRK1: neurotrophic tyrosine kinase, receptor, type 1
- OCRL: oculocerebrorenal syndrome of Lowe
- OPA1: optic atrophy 1 (autosomal dominant)
- OTX2: orthodenticle homeobox 2
- PAFAH1B1: platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
- PARK2: parkinson protein 2, E3 ubiquitin protein ligase (parkin)
- PARK7: parkinson protein 7
- PAX8: paired box 8
- PCSK9: proprotein convertase subtilisin/kexin type 9
- PDCD10: programmed cell death 10
- PDGFB: platelet-derived growth factor beta polypeptide
- PDGFRA: platelet-derived growth factor receptor, alpha polypeptide
- PDGFRB: platelet-derived growth factor receptor, beta polypeptide
- PINK1: PTEN induced putative kinase 1
- PKD2: polycystic kidney disease 2 (autosomal dominant)
- PML: promyelocytic leukemia
- PRICKLE1: prickle homolog 1 (Drosophila)
- PRKAR1A: protein kinase, cAMP-dependent, regulatory, type I, alpha
- PRNP: prion protein
- PROK2: prokineticin 2
- PTCH1: patched 1
- PTEN: phosphatase and tensin homolog
- PTPN11: protein tyrosine phosphatase, non-receptor type 11
- PTPN22: protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
- RAB7A: RAB7A, member RAS oncogene family
- RAF1: v-raf-1 murine leukemia viral oncogene homolog 1
- RASA1: RAS p21 protein activator (GTPase activating protein) 1
- REN: renin
- RET: ret proto-oncogene
- SALL1: sal-like 1 (Drosophila)
- SHANK3: SH3 and multiple ankyrin repeat domains 3
- SHH: sonic hedgehog
- SKI: v-ski sarcoma viral oncogene homolog (avian)
- SLC25A4: solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4
- SLC2A1: solute carrier family 2 (facilitated glucose transporter), member 1
- SMAD3: SMAD family member 3
- SMAD4: SMAD family member 4
- SMPD1: sphingomyelin phosphodiesterase 1, acid lysosomal
- SNAI2: snail homolog 2 (Drosophila)
- SNCA: synuclein, alpha (non A4 component of amyloid precursor)
- SNCAIP: synuclein, alpha interacting protein
- SOD1: superoxide dismutase 1, soluble
- SOS1: son of sevenless homolog 1 (Drosophila)
- SOST: sclerostin
- SOX2: SRY (sex determining region Y)-box 2
- SOX9: SRY (sex determining region Y)-box 9
- SPRED1: sprouty-related, EVH1 domain containing 1
- SQSTM1: sequestosome 1
- STAT3: signal transducer and activator of transcription 3 (acute-phase response factor)
- STK11: serine/threonine kinase 11
- TBX1: T-box 1
- TEK: TEK tyrosine kinase, endothelial
- TFAP2B: transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
- TGFB1: transforming growth factor, beta 1
- TGFBR1: transforming growth factor, beta receptor 1
- TGFBR2: transforming growth factor, beta receptor II (70/80kDa)
- TMEM127: transmembrane protein 127
- TNFRSF11A: tumor necrosis factor receptor superfamily, member 11a, NFKB activator
- TNFRSF1A: tumor necrosis factor receptor superfamily, member 1A
- TP53: tumor protein p53
- TP63: tumor protein p63
- TSC1: tuberous sclerosis 1
- TSC2: tuberous sclerosis 2
- TWIST1: twist basic helix-loop-helix transcription factor 1
- UCHL1: ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
- WNT4: wingless-type MMTV integration site family, member 4
- XIAP: X-linked inhibitor of apoptosis
- YWHAE: tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide
Source: Gene Ontology Consortium
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