Cellular component organization

Cellular component organization

• AASS: aminoadipate-semialdehyde synthase
• ABCA1: ATP-binding cassette, sub-family A (ABC1), member 1
• ABCD1: ATP-binding cassette, sub-family D (ALD), member 1
• ACTA1: actin, alpha 1, skeletal muscle
• ACTB: actin, beta
• ACTG1: actin, gamma 1
• ACVRL1: activin A receptor type II-like 1
• ADAMTS2: ADAM metallopeptidase with thrombospondin type 1 motif, 2
• AGT: angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
• AGTR1: angiotensin II receptor, type 1
• AGXT: alanine-glyoxylate aminotransferase
• AKT1: v-akt murine thymoma viral oncogene homolog 1
• ALAD: aminolevulinate dehydratase
• ALDH5A1: aldehyde dehydrogenase 5 family, member A1
• ALDOB: aldolase B, fructose-bisphosphate
• ALMS1: Alstrom syndrome 1
• ALS2: amyotrophic lateral sclerosis 2 (juvenile)
• AMELX: amelogenin, X-linked
• ANG: angiogenin, ribonuclease, RNase A family, 5
• ANK1: ankyrin 1, erythrocytic
• ANK2: ankyrin 2, neuronal
• APC: adenomatous polyposis coli
• APOA1: apolipoprotein A-I
• APOB: apolipoprotein B
• APOE: apolipoprotein E
• APP: amyloid beta (A4) precursor protein
• AR: androgen receptor
• ARFGEF2: ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)
• ARID1A: AT rich interactive domain 1A (SWI-like)
• ARID1B: AT rich interactive domain 1B (SWI1-like)
• ARSB: arylsulfatase B
• ATG16L1: autophagy related 16-like 1 (S. cerevisiae)
• ATL1: atlastin GTPase 1
• ATM: ataxia telangiectasia mutated
• ATP2A1: ATPase, Ca++ transporting, cardiac muscle, fast twitch 1
• ATP2C1: ATPase, Ca++ transporting, type 2C, member 1
• ATP6V0A2: ATPase, H+ transporting, lysosomal V0 subunit a2
• ATP7A: ATPase, Cu++ transporting, alpha polypeptide
• ATP8B1: ATPase, aminophospholipid transporter, class I, type 8B, member 1
• ATXN2: ataxin 2
• ATXN3: ataxin 3
• AVP: arginine vasopressin
• BBS1: Bardet-Biedl syndrome 1
• BBS10: Bardet-Biedl syndrome 10
• BCOR: BCL6 corepressor
• BDNF: brain-derived neurotrophic factor
• BLM: Bloom syndrome, RecQ helicase-like
• BMPR2: bone morphogenetic protein receptor, type II (serine/threonine kinase)
• BRCA1: breast cancer 1, early onset
• BRCA2: breast cancer 2, early onset
• BSCL2: Berardinelli-Seip congenital lipodystrophy 2 (seipin)
• C10orf2: chromosome 10 open reading frame 2
• CACNA1C: calcium channel, voltage-dependent, L type, alpha 1C subunit
• CACNA1S: calcium channel, voltage-dependent, L type, alpha 1S subunit
• CACNB4: calcium channel, voltage-dependent, beta 4 subunit
• CAPN3: calpain 3, (p94)
• CASQ2: calsequestrin 2 (cardiac muscle)
• CAV3: caveolin 3
• CDAN1: codanin 1
• CDC73: cell division cycle 73
• CDH1: cadherin 1, type 1, E-cadherin (epithelial)
• CDH23: cadherin-related 23
• CDKL5: cyclin-dependent kinase-like 5
• CEP290: centrosomal protein 290kDa
• CHEK2: checkpoint kinase 2
• CHMP2B: charged multivesicular body protein 2B
• CHN1: chimerin 1
• CHRNB2: cholinergic receptor, nicotinic, beta 2 (neuronal)
• CLDN14: claudin 14
• CLN3: ceroid-lipofuscinosis, neuronal 3
• CLRN1: clarin 1
• COCH: cochlin
• COL11A1: collagen, type XI, alpha 1
• COL11A2: collagen, type XI, alpha 2
• COL17A1: collagen, type XVII, alpha 1
• COL18A1: collagen, type XVIII, alpha 1
• COL1A1: collagen, type I, alpha 1
• COL1A2: collagen, type I, alpha 2
• COL2A1: collagen, type II, alpha 1
• COL3A1: collagen, type III, alpha 1
• COL4A1: collagen, type IV, alpha 1
• COL4A3: collagen, type IV, alpha 3 (Goodpasture antigen)
• COL4A4: collagen, type IV, alpha 4
• COL4A5: collagen, type IV, alpha 5
• COL5A1: collagen, type V, alpha 1
• COL5A2: collagen, type V, alpha 2
• COL6A1: collagen, type VI, alpha 1
• COL6A2: collagen, type VI, alpha 2
• COL6A3: collagen, type VI, alpha 3
• COL7A1: collagen, type VII, alpha 1
• COL8A2: collagen, type VIII, alpha 2
• COL9A1: collagen, type IX, alpha 1
• COL9A2: collagen, type IX, alpha 2
• COL9A3: collagen, type IX, alpha 3
• CREBBP: CREB binding protein
• CRTAP: cartilage associated protein
• CSF1R: colony stimulating factor 1 receptor
• CST3: cystatin C
• CTDP1: CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
• CTNNB1: catenin (cadherin-associated protein), beta 1, 88kDa
• CUL7: cullin 7
• CYBA: cytochrome b-245, alpha polypeptide
• CYBB: cytochrome b-245, beta polypeptide
• CYLD: cylindromatosis (turban tumor syndrome)
• DARS2: aspartyl-tRNA synthetase 2, mitochondrial
• DCTN1: dynactin 1
• DCX: doublecortin
• DES: desmin
• DFNB31: deafness, autosomal recessive 31
• DICER1: dicer 1, ribonuclease type III
• DKC1: dyskeratosis congenita 1, dyskerin
• DMD: dystrophin
• DMPK: dystrophia myotonica-protein kinase
• DNAJC19: DnaJ (Hsp40) homolog, subfamily C, member 19
• DNM2: dynamin 2
• DNMT1: DNA (cytosine-5-)-methyltransferase 1
• DRD3: dopamine receptor D3
• DYNC1H1: dynein, cytoplasmic 1, heavy chain 1
• EDN3: endothelin 3
• EFEMP2: EGF containing fibulin-like extracellular matrix protein 2
• EHMT1: euchromatic histone-lysine N-methyltransferase 1
• ELANE: elastase, neutrophil expressed
• ELN: elastin
• EMD: emerin
• ENG: endoglin
• EP300: E1A binding protein p300
• ERBB2: v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)
• EYA1: eyes absent homolog 1 (Drosophila)
• EZH2: enhancer of zeste homolog 2 (Drosophila)
• FANCA: Fanconi anemia, complementation group A
• FANCC: Fanconi anemia, complementation group C
• FANCG: Fanconi anemia, complementation group G
• FAS: Fas cell surface death receptor
• FBLN5: fibulin 5
• FBN1: fibrillin 1
• FBN2: fibrillin 2
• FGD1: FYVE, RhoGEF and PH domain containing 1
• FGD4: FYVE, RhoGEF and PH domain containing 4
• FGFR1: fibroblast growth factor receptor 1
• FGFR2: fibroblast growth factor receptor 2
• FGFR4: fibroblast growth factor receptor 4
• FGFRL1: fibroblast growth factor receptor-like 1
• FLCN: folliculin
• FLNA: filamin A, alpha
• FLNB: filamin B, beta
• FOXC1: forkhead box C1
• FOXC2: forkhead box C2 (MFH-1, mesenchyme forkhead 1)
• FOXG1: forkhead box G1
• FOXL2: forkhead box L2
• FOXP3: forkhead box P3
• FRMD7: FERM domain containing 7
• FTL: ferritin, light polypeptide
• FXN: frataxin
• FZD4: frizzled family receptor 4
• GAA: glucosidase, alpha; acid
• GATA1: GATA binding protein 1 (globin transcription factor 1)
• GCH1: GTP cyclohydrolase 1
• GDAP1: ganglioside induced differentiation associated protein 1
• GJA1: gap junction protein, alpha 1, 43kDa
• GJB1: gap junction protein, beta 1, 32kDa
• GJB2: gap junction protein, beta 2, 26kDa
• GNMT: glycine N-methyltransferase
• GPR143: G protein-coupled receptor 143
• GPR98: G protein-coupled receptor 98
• GRHPR: glyoxylate reductase/hydroxypyruvate reductase
• GSN: gelsolin
• HAX1: HCLS1 associated protein X-1
• HBA2: hemoglobin, alpha 2
• HBB: hemoglobin, beta
• HFE: hemochromatosis
• HFE2: hemochromatosis type 2 (juvenile)
• HGSNAT: heparan-alpha-glucosaminide N-acetyltransferase
• HLCS: holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase)
• HMGCL: 3-hydroxymethyl-3-methylglutaryl-CoA lyase
• HPRT1: hypoxanthine phosphoribosyltransferase 1
• HPS1: Hermansky-Pudlak syndrome 1
• HRAS: v-Ha-ras Harvey rat sarcoma viral oncogene homolog
• HTT: huntingtin
• IGF2: insulin-like growth factor 2 (somatomedin A)
• IGHMBP2: immunoglobulin mu binding protein 2
• IKBKAP: inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein
• IL1A: interleukin 1, alpha
• INS: insulin
• ISCU: iron-sulfur cluster scaffold homolog (E. coli)
• ITGA6: integrin, alpha 6
• ITGB4: integrin, beta 4
• JAK2: Janus kinase 2
• KAL1: Kallmann syndrome 1 sequence
• KANSL1: KAT8 regulatory NSL complex subunit 1
• KAT6B: K(lysine) acetyltransferase 6B
• KCNJ2: potassium inwardly-rectifying channel, subfamily J, member 2
• KCNQ2: potassium voltage-gated channel, KQT-like subfamily, member 2
• KCNQ3: potassium voltage-gated channel, KQT-like subfamily, member 3
• KIT: v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
• KMT2D: lysine (K)-specific methyltransferase 2D
• KRAS: v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog
• KRT14: keratin 14
• KRT16: keratin 16
• KRT3: keratin 3
• KRT5: keratin 5
• KRT6C: keratin 6C
• KRT86: keratin 86
• L1CAM: L1 cell adhesion molecule
• LAMA3: laminin, alpha 3
• LAMB3: laminin, beta 3
• LAMC2: laminin, gamma 2
• LDLRAP1: low density lipoprotein receptor adaptor protein 1
• LEPRE1: leucine proline-enriched proteoglycan (leprecan) 1
• LETM1: leucine zipper-EF-hand containing transmembrane protein 1
• LGI1: leucine-rich, glioma inactivated 1
• LIMK1: LIM domain kinase 1
• LMNA: lamin A/C
• LPL: lipoprotein lipase
• LRP5: low density lipoprotein receptor-related protein 5
• LRRK2: leucine-rich repeat kinase 2
• LYST: lysosomal trafficking regulator
• MAP2K1: mitogen-activated protein kinase kinase 1
• MAP2K2: mitogen-activated protein kinase kinase 2
• MAPT: microtubule-associated protein tau
• MEN1: multiple endocrine neoplasia I
• MFN2: mitofusin 2
• MID1: midline 1 (Opitz/BBB syndrome)
• MITF: microphthalmia-associated transcription factor
• MKKS: McKusick-Kaufman syndrome
• MLC1: megalencephalic leukoencephalopathy with subcortical cysts 1
• MMP20: matrix metallopeptidase 20
• MPV17: MpV17 mitochondrial inner membrane protein
• MSH2: mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli)
• MSX1: msh homeobox 1
• MTM1: myotubularin 1
• MTMR2: myotubularin related protein 2
• MUC1: mucin 1, cell surface associated
• MYH9: myosin, heavy chain 9, non-muscle
• MYO6: myosin VI
• MYO7A: myosin VIIA
• NBN: nibrin
• NCF1: neutrophil cytosolic factor 1
• NCF2: neutrophil cytosolic factor 2
• NCF4: neutrophil cytosolic factor 4, 40kDa
• NDP: Norrie disease (pseudoglioma)
• NEB: nebulin
• NEFL: neurofilament, light polypeptide
• NF1: neurofibromin 1
• NF2: neurofibromin 2 (merlin)
• NGF: nerve growth factor (beta polypeptide)
• NIPBL: Nipped-B homolog (Drosophila)
• NLRP3: NLR family, pyrin domain containing 3
• NOD2: nucleotide-binding oligomerization domain containing 2
• NOG: noggin
• NRAS: neuroblastoma RAS viral (v-ras) oncogene homolog
• NSD1: nuclear receptor binding SET domain protein 1
• NTRK1: neurotrophic tyrosine kinase, receptor, type 1
• OAT: ornithine aminotransferase
• OCRL: oculocerebrorenal syndrome of Lowe
• OFD1: oral-facial-digital syndrome 1
• OPA1: optic atrophy 1 (autosomal dominant)
• OTOF: otoferlin
• OTX2: orthodenticle homeobox 2
• PAFAH1B1: platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
• PARK2: parkinson protein 2, E3 ubiquitin protein ligase (parkin)
• PARK7: parkinson protein 7
• PAX2: paired box 2
• PAX8: paired box 8
• PCDH15: protocadherin-related 15
• PCNT: pericentrin
• PCSK9: proprotein convertase subtilisin/kexin type 9
• PDGFB: platelet-derived growth factor beta polypeptide
• PDGFRA: platelet-derived growth factor receptor, alpha polypeptide
• PDGFRB: platelet-derived growth factor receptor, beta polypeptide
• PEX1: peroxisomal biogenesis factor 1
• PEX7: peroxisomal biogenesis factor 7
• PHOX2B: paired-like homeobox 2b
• PINK1: PTEN induced putative kinase 1
• PKD2: polycystic kidney disease 2 (autosomal dominant)
• PKHD1: polycystic kidney and hepatic disease 1 (autosomal recessive)
• PKP2: plakophilin 2
• PLEC: plectin
• PLG: plasminogen
• PLOD1: procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1
• PML: promyelocytic leukemia
• PPP1R12A: protein phosphatase 1, regulatory subunit 12A
• PPT1: palmitoyl-protein thioesterase 1
• PRF1: perforin 1 (pore forming protein)
• PRKAG2: protein kinase, AMP-activated, gamma 2 non-catalytic subunit
• PRNP: prion protein
• PRSS1: protease, serine, 1 (trypsin 1)
• PTCH1: patched 1
• PTEN: phosphatase and tensin homolog
• PTPN11: protein tyrosine phosphatase, non-receptor type 11
• RAB23: RAB23, member RAS oncogene family
• RAB7A: RAB7A, member RAS oncogene family
• RAD50: RAD50 homolog (S. cerevisiae)
• RAD51: RAD51 homolog (S. cerevisiae)
• RAF1: v-raf-1 murine leukemia viral oncogene homolog 1
• RASA1: RAS p21 protein activator (GTPase activating protein) 1
• RB1: retinoblastoma 1
• RET: ret proto-oncogene
• ROBO3: roundabout, axon guidance receptor, homolog 3 (Drosophila)
• RPGR: retinitis pigmentosa GTPase regulator
• RPL11: ribosomal protein L11
• RPL35A: ribosomal protein L35a
• RPL5: ribosomal protein L5
• RPS10: ribosomal protein S10
• RPS17: ribosomal protein S17
• RPS19: ribosomal protein S19
• RPS24: ribosomal protein S24
• RPS26: ribosomal protein S26
• RPS6KA3: ribosomal protein S6 kinase, 90kDa, polypeptide 3
• RPS7: ribosomal protein S7
• SACS: spastic ataxia of Charlevoix-Saguenay (sacsin)
• SALL1: sal-like 1 (Drosophila)
• SAR1B: SAR1 homolog B (S. cerevisiae)
• SBDS: Shwachman-Bodian-Diamond syndrome
• SEPT9: septin 9
• SHANK3: SH3 and multiple ankyrin repeat domains 3
• SHH: sonic hedgehog
• SKI: v-ski sarcoma viral oncogene homolog (avian)
• SLC25A4: solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4
• SLC2A1: solute carrier family 2 (facilitated glucose transporter), member 1
• SLC7A7: solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
• SLC7A9: solute carrier family 7 (glycoprotein-associated amino acid transporter light chain, bo,+ system), member 9
• SMAD3: SMAD family member 3
• SMAD4: SMAD family member 4
• SMARCA4: SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
• SMARCB1: SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1
• SMARCE1: SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1
• SMC1A: structural maintenance of chromosomes 1A
• SMC3: structural maintenance of chromosomes 3
• SMN2: survival of motor neuron 2, centromeric
• SNAI2: snail family zinc finger 2
• SNCA: synuclein, alpha (non A4 component of amyloid precursor)
• SNCAIP: synuclein, alpha interacting protein
• SOD1: superoxide dismutase 1, soluble
• SOS1: son of sevenless homolog 1 (Drosophila)
• SOST: sclerostin
• SOX2: SRY (sex determining region Y)-box 2
• SOX9: SRY (sex determining region Y)-box 9
• SPAST: spastin
• SRCAP: Snf2-related CREBBP activator protein
• STK11: serine/threonine kinase 11
• STRC: stereocilin
• SURF1: surfeit 1
• SYNE1: spectrin repeat containing, nuclear envelope 1
• TAF1: TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
• TAZ: tafazzin
• TBX5: T-box 5
• TCF4: transcription factor 4
• TCIRG1: T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3
• TEK: TEK tyrosine kinase, endothelial
• TERT: telomerase reverse transcriptase
• TET2: tet methylcytosine dioxygenase 2
• TGFB1: transforming growth factor, beta 1
• TGFBR1: transforming growth factor, beta receptor 1
• TGM1: transglutaminase 1 (K polypeptide epidermal type I, protein-glutamine-gamma-glutamyltransferase)
• TIMM8A: translocase of inner mitochondrial membrane 8 homolog A (yeast)
• TINF2: TERF1 (TRF1)-interacting nuclear factor 2
• TNXB: tenascin XB
• TOR1A: torsin family 1, member A (torsin A)
• TP53: tumor protein p53
• TP63: tumor protein p63
• TREM2: triggering receptor expressed on myeloid cells 2
• TRIOBP: TRIO and F-actin binding protein
• TRPV4: transient receptor potential cation channel, subfamily V, member 4
• TSC1: tuberous sclerosis 1
• TSC2: tuberous sclerosis 2
• TTN: titin
• TWIST1: twist basic helix-loop-helix transcription factor 1
• TYMP: thymidine phosphorylase
• TYROBP: TYRO protein tyrosine kinase binding protein
• USH1C: Usher syndrome 1C (autosomal recessive, severe)
• USH1G: Usher syndrome 1G (autosomal recessive)
• USH2A: Usher syndrome 2A (autosomal recessive, mild)
• VCP: valosin containing protein
• VHL: von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase
• VLDLR: very low density lipoprotein receptor
• VRK1: vaccinia related kinase 1
• VWF: von Willebrand factor
• WAS: Wiskott-Aldrich syndrome
• WNT3: wingless-type MMTV integration site family, member 3
• WNT4: wingless-type MMTV integration site family, member 4
• WRN: Werner syndrome, RecQ helicase-like
• WT1: Wilms tumor 1
• XPC: xeroderma pigmentosum, complementation group C
• YWHAE: tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide

Source: Gene Ontology Consortium.