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- D-2-hydroxyglutarate dehydrogenase: D2HGDH
- deafness, autosomal dominant 5: DFNA5
- deafness, autosomal recessive 31: DFNB31
- deafness, autosomal recessive 59: DFNB59
- decorin: DCN
- 7-dehydrocholesterol reductase: DHCR7
- delta-like 3 (Drosophila): DLL3
- dentin sialophosphoprotein: DSPP
- deoxyguanosine kinase: DGUOK
- desert hedgehog: DHH
- desmin: DES
- desmoglein 4: DSG4
- dihydrolipoamide branched chain transacylase E2: DBT
- dihydrolipoamide dehydrogenase: DLD
- dihydrolipoamide S-acetyltransferase: DLAT
- dihydroorotate dehydrogenase (quinone): DHODH
- dihydropyrimidine dehydrogenase: DPYD
- DIRAS family, GTP-binding RAS-like 3: DIRAS3
- DNA (cytosine-5-)-methyltransferase 1: DNMT1
- DnaJ (Hsp40) homolog, subfamily C, member 19: DNAJC19
- docking protein 7: DOK7
- dopa decarboxylase (aromatic L-amino acid decarboxylase): DDC
- dopamine beta-hydroxylase (dopamine beta-monooxygenase): DBH
- dopamine receptor D3: DRD3
- dopamine receptor D5: DRD5
- doublecortin: DCX
- dual oxidase 2: DUOX2
- dynactin 1: DCTN1
- dynamin 2: DNM2
- dynein, axonemal, heavy chain 5: DNAH5
- dynein, axonemal, intermediate chain 1: DNAI1
- dynein, cytoplasmic 1, heavy chain 1: DYNC1H1
- dysferlin, limb girdle muscular dystrophy 2B (autosomal recessive): DYSF
- dyskeratosis congenita 1, dyskerin: DKC1
- dystrophia myotonica-protein kinase: DMPK
- dystrophin: DMD
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