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- iduronate 2-sulfatase: IDS
- iduronidase, alpha-L-: IDUA
- immunity-related GTPase family, M: IRGM
- immunoglobulin mu binding protein 2: IGHMBP2
- inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein: IKBKAP
- inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma: IKBKG
- inositol-trisphosphate 3-kinase C: ITPKC
- insulin: INS
- insulin-like growth factor 2 (somatomedin A): IGF2
- integral membrane protein 2B: ITM2B
- integrin, alpha 6: ITGA6
- integrin, beta 4: ITGB4
- interferon regulatory factor 5: IRF5
- interferon regulatory factor 6: IRF6
- interleukin 1, alpha: IL1A
- interleukin-1 receptor-associated kinase 4: IRAK4
- interleukin 2 receptor, gamma: IL2RG
- interleukin 7 receptor: IL7R
- interleukin 23 receptor: IL23R
- intraflagellar transport 80 homolog (Chlamydomonas): IFT80
- intraflagellar transport 140 homolog (Chlamydomonas): IFT140
- iron-sulfur cluster scaffold homolog (E. coli): ISCU
- isovaleryl-CoA dehydrogenase: IVD
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