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- D2HGDH: D-2-hydroxyglutarate dehydrogenase
- DARS2: aspartyl-tRNA synthetase 2, mitochondrial
- DBH: dopamine beta-hydroxylase (dopamine beta-monooxygenase)
- DBT: dihydrolipoamide branched chain transacylase E2
- DCN: decorin
- DCTN1: dynactin 1
- DCX: doublecortin
- DDC: dopa decarboxylase (aromatic L-amino acid decarboxylase)
- DES: desmin
- DFNA5: deafness, autosomal dominant 5
- DFNB31: deafness, autosomal recessive 31
- DFNB59: deafness, autosomal recessive 59
- DGUOK: deoxyguanosine kinase
- DHCR7: 7-dehydrocholesterol reductase
- DHH: desert hedgehog
- DHODH: dihydroorotate dehydrogenase (quinone)
- DICER1: dicer 1, ribonuclease type III
- DIRAS3: DIRAS family, GTP-binding RAS-like 3
- DKC1: dyskeratosis congenita 1, dyskerin
- DLAT: dihydrolipoamide S-acetyltransferase
- DLD: dihydrolipoamide dehydrogenase
- DLL3: delta-like 3 (Drosophila)
- DMD: dystrophin
- DMPK: dystrophia myotonica-protein kinase
- DNAH5: dynein, axonemal, heavy chain 5
- DNAI1: dynein, axonemal, intermediate chain 1
- DNAJC19: DnaJ (Hsp40) homolog, subfamily C, member 19
- DNM2: dynamin 2
- DNMT1: DNA (cytosine-5-)-methyltransferase 1
- DOK7: docking protein 7
- DPYD: dihydropyrimidine dehydrogenase
- DRD3: dopamine receptor D3
- DRD5: dopamine receptor D5
- DSG4: desmoglein 4
- DSPP: dentin sialophosphoprotein
- DUOX2: dual oxidase 2
- DYNC1H1: dynein, cytoplasmic 1, heavy chain 1
- DYSF: dysferlin, limb girdle muscular dystrophy 2B (autosomal recessive)
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