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References

These sources were used to develop the Genetics Home Reference condition summary on factor V Leiden thrombophilia.

Calderwood CJ, Greer IA. The role of factor V Leiden in maternal health and the outcome of pregnancy. Curr Drug Targets. 2005 Aug;6(5):567-76. Review. PubMed citation
Gene Review: Factor V Leiden Thrombophilia
Horne MK 3rd, McCloskey DJ. Factor V Leiden as a common genetic risk factor for venous thromboembolism. J Nurs Scholarsh. 2006;38(1):19-25. Review. PubMed citation
Juul K, Tybjaerg-Hansen A, Schnohr P, Nordestgaard BG. Factor V Leiden and the risk for venous thromboembolism in the adult Danish population. Ann Intern Med. 2004 Mar 2;140(5):330-7. PubMed citation
Major DA, Sane DC, Herrington DM. Cardiovascular implications of the factor V Leiden mutation. Am Heart J. 2000 Aug;140(2):189-95. Review. PubMed citation
Mann KG, Kalafatis M. Factor V: a combination of Dr Jekyll and Mr Hyde. Blood. 2003 Jan 1;101(1):20-30. Epub 2002 Aug 8. Review. PubMed citation
Ornstein DL, Cushman M. Cardiology patient page. Factor V Leiden. Circulation. 2003 Apr 22;107(15):e94-7. PubMed citation
Rosendaal FR, Reitsma PH. Genetics of venous thrombosis. J Thromb Haemost. 2009 Jul;7 Suppl 1:301-4. doi: 10.1111/j.1538-7836.2009.03394.x. Review. PubMed citation
Rosendorff A, Dorfman DM. Activated protein C resistance and factor V Leiden: a review. Arch Pathol Lab Med. 2007 Jun;131(6):866-71. Review. PubMed citation
Segal JB, Brotman DJ, Necochea AJ, Emadi A, Samal L, Wilson LM, Crim MT, Bass EB. Predictive value of factor V Leiden and prothrombin G20210A in adults with venous thromboembolism and in family members of those with a mutation: a systematic review. JAMA. 2009 Jun 17;301(23):2472-85. doi: 10.1001/jama.2009.853. Review. PubMed citation


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