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Reviewed September 2008
What is the official name of the ABCD1 gene?
The official name of this gene is “ATP-binding cassette, sub-family D (ALD), member 1.”
ABCD1 is the gene's official symbol. The ABCD1 gene is also known by other names, listed below.
Read more about gene names and symbols on the About page.
What is the normal function of the ABCD1 gene?
The ABCD1 gene provides instructions for producing the adrenoleukodystrophy protein (ALDP). ALDP is one component of a transport protein that is located in the membrane surrounding peroxisomes. Peroxisomes are small sacs within cells that process many types of molecules. ALDP is called a "half-transporter" because it needs to join with another identical or closely related protein in order to form a complete, functional transport protein. Although the exact function of this protein has not been determined, it may transport a molecule necessary for the breakdown of very long-chain fatty acids (VLCFAs) in peroxisomes.
Does the ABCD1 gene share characteristics with other genes?
A gene family is a group of genes that share important characteristics. Classifying individual genes into families helps researchers describe how genes are related to each other. For more information, see What are gene families? in the Handbook.
How are changes in the ABCD1 gene related to health conditions?
Where is the ABCD1 gene located?
Cytogenetic Location: Xq28
Molecular Location on the X chromosome: base pairs 152,990,322 to 153,010,215
The ABCD1 gene is located on the long (q) arm of the X chromosome at position 28.
More precisely, the ABCD1 gene is located from base pair 152,990,322 to base pair 153,010,215 on the X chromosome.
See How do geneticists indicate the location of a gene? in the Handbook.
Where can I find additional information about ABCD1?
You and your healthcare professional may find the following resources about ABCD1 helpful.
You may also be interested in these resources, which are designed for genetics professionals and researchers.
What other names do people use for the ABCD1 gene or gene products?
See How are genetic conditions and genes named? in the Handbook.
Where can I find general information about genes?
The Handbook provides basic information about genetics in clear language.
These links provide additional genetics resources that may be useful.
What glossary definitions help with understanding ABCD1?
You may find definitions for these and many other terms in the Genetics Home Reference Glossary.
See also Understanding Medical Terminology.
References (9 links)
The resources on this site should not be used as a substitute for professional medical care or advice. Users seeking information about a personal genetic disease, syndrome, or condition should consult with a qualified healthcare professional. See How can I find a genetics professional in my area? in the Handbook.