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Reviewed October 2008
What is the official name of the ADAMTS10 gene?
The official name of this gene is “ADAM metallopeptidase with thrombospondin type 1 motif, 10.”
ADAMTS10 is the gene's official symbol. The ADAMTS10 gene is also known by other names, listed below.
Read more about gene names and symbols on the About page.
What is the normal function of the ADAMTS10 gene?
The ADAMTS10 gene provides instructions for making an enzyme that is found in many of the body's cells and tissues. This enzyme is part of a family of metalloproteases, which are zinc-containing enzymes that cut apart other proteins. Although the function of the ADAMTS10 enzyme is unknown, it is critical for growth before and after birth. Researchers believe that it may be involved in the development of structures including the skin, eyes, heart, and skeleton.
Does the ADAMTS10 gene share characteristics with other genes?
The ADAMTS10 gene belongs to a family of genes called ADAMTS (ADAMTS metallopeptidase with thrombospondin type 1 motif family).
A gene family is a group of genes that share important characteristics. Classifying individual genes into families helps researchers describe how genes are related to each other. For more information, see What are gene families? in the Handbook.
How are changes in the ADAMTS10 gene related to health conditions?
Where is the ADAMTS10 gene located?
Cytogenetic Location: 19p13.2
Molecular Location on chromosome 19: base pairs 8,645,125 to 8,675,587
The ADAMTS10 gene is located on the short (p) arm of chromosome 19 at position 13.2.
More precisely, the ADAMTS10 gene is located from base pair 8,645,125 to base pair 8,675,587 on chromosome 19.
See How do geneticists indicate the location of a gene? in the Handbook.
Where can I find additional information about ADAMTS10?
You and your healthcare professional may find the following resources about ADAMTS10 helpful.
You may also be interested in these resources, which are designed for genetics professionals and researchers.
What other names do people use for the ADAMTS10 gene or gene products?
See How are genetic conditions and genes named? in the Handbook.
Where can I find general information about genes?
The Handbook provides basic information about genetics in clear language.
These links provide additional genetics resources that may be useful.
What glossary definitions help with understanding ADAMTS10?
You may find definitions for these and many other terms in the Genetics Home Reference Glossary.
See also Understanding Medical Terminology.
References (5 links)
The resources on this site should not be used as a substitute for professional medical care or advice. Users seeking information about a personal genetic disease, syndrome, or condition should consult with a qualified healthcare professional. See How can I find a genetics professional in my area? in the Handbook.