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Reviewed March 2008
What is the official name of the CLIP2 gene?
The official name of this gene is “CAP-GLY domain containing linker protein 2.”
CLIP2 is the gene's official symbol. The CLIP2 gene is also known by other names, listed below.
Read more about gene names and symbols on the About page.
What is the normal function of the CLIP2 gene?
The CLIP2 gene provides instructions for making a protein called CAP-GLY domain containing linker protein 2. The protein is also known as CLIP-115. This protein is found predominantly in the brain, where it likely plays a role in the normal structure and function of nerve cells. Within cells, this protein is thought to regulate aspects of the cytoskeleton, the structural framework that helps to determine cell shape, size, and movement. The protein is associated with microtubules, which are rigid, hollow fibers that make up a significant part of the cytoskeleton. Microtubules help cells maintain their shape, assist in the process of cell division, and are essential for the transport of materials within cells.
How are changes in the CLIP2 gene related to health conditions?
Where is the CLIP2 gene located?
Cytogenetic Location: 7q11.23
Molecular Location on chromosome 7: base pairs 74,289,474 to 74,405,942
The CLIP2 gene is located on the long (q) arm of chromosome 7 at position 11.23.
More precisely, the CLIP2 gene is located from base pair 74,289,474 to base pair 74,405,942 on chromosome 7.
See How do geneticists indicate the location of a gene? in the Handbook.
Where can I find additional information about CLIP2?
You and your healthcare professional may find the following resources about CLIP2 helpful.
You may also be interested in these resources, which are designed for genetics professionals and researchers.
What other names do people use for the CLIP2 gene or gene products?
See How are genetic conditions and genes named? in the Handbook.
Where can I find general information about genes?
The Handbook provides basic information about genetics in clear language.
These links provide additional genetics resources that may be useful.
What glossary definitions help with understanding CLIP2?
You may find definitions for these and many other terms in the Genetics Home Reference Glossary.
See also Understanding Medical Terminology.
References (6 links)
The resources on this site should not be used as a substitute for professional medical care or advice. Users seeking information about a personal genetic disease, syndrome, or condition should consult with a qualified healthcare professional. See How can I find a genetics professional in my area? in the Handbook.