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Reviewed August 2013
What is the official name of the CLN5 gene?
The official name of this gene is “ceroid-lipofuscinosis, neuronal 5.”
CLN5 is the gene's official symbol. The CLN5 gene is also known by other names, listed below.
Read more about gene names and symbols on the About page.
What is the normal function of the CLN5 gene?
The CLN5 gene provides instructions for making a protein whose function is unknown. When produced, the CLN5 protein has extra protein segments attached and is inactive. This form is called a preprotein. For the CLN5 protein to become active, the additional segments must be removed from the preprotein, followed by additional processing steps. The active CLN5 protein is found in cell compartments called lysosomes, which digest and recycle different types of molecules.
How are changes in the CLN5 gene related to health conditions?
Genetics Home Reference provides information about these additional conditions, which are also associated with changes in the CLN5 gene:
Where is the CLN5 gene located?
Cytogenetic Location: 13q21.1-q32
Molecular Location on chromosome 13: base pairs 76,991,923 to 77,002,516
The CLN5 gene is located on the long (q) arm of chromosome 13 between positions 21.1 and 32.
More precisely, the CLN5 gene is located from base pair 76,991,923 to base pair 77,002,516 on chromosome 13.
See How do geneticists indicate the location of a gene? in the Handbook.
Where can I find additional information about CLN5?
You and your healthcare professional may find the following resources about CLN5 helpful.
You may also be interested in these resources, which are designed for genetics professionals and researchers.
What other names do people use for the CLN5 gene or gene products?
See How are genetic conditions and genes named? in the Handbook.
Where can I find general information about genes?
The Handbook provides basic information about genetics in clear language.
These links provide additional genetics resources that may be useful.
What glossary definitions help with understanding CLN5?
You may find definitions for these and many other terms in the Genetics Home Reference Glossary.
See also Understanding Medical Terminology.
References (5 links)
The resources on this site should not be used as a substitute for professional medical care or advice. Users seeking information about a personal genetic disease, syndrome, or condition should consult with a qualified healthcare professional. See How can I find a genetics professional in my area? in the Handbook.