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Reviewed December 2013
What is the official name of the FOXG1 gene?
The official name of this gene is “forkhead box G1.”
FOXG1 is the gene's official symbol. The FOXG1 gene is also known by other names, listed below.
Read more about gene names and symbols on the About page.
What is the normal function of the FOXG1 gene?
The FOXG1 gene provides instructions for making a protein known as forkhead box G1. This protein is a transcription factor, which means it helps regulate the activity of other genes. Specifically, the forkhead box G1 protein acts as a transcriptional repressor, turning off (repressing) the activity of certain genes when they are not needed. Researchers believe that this protein plays an important role in brain development, particularly in a region of the embryonic brain known as the telencephalon. The telencephalon ultimately develops into several critical structures, including the two cerebral hemispheres (which control most voluntary activity, language, sensory perception, learning, and memory).
Does the FOXG1 gene share characteristics with other genes?
The FOXG1 gene belongs to a family of genes called FOX (forkhead box genes).
A gene family is a group of genes that share important characteristics. Classifying individual genes into families helps researchers describe how genes are related to each other. For more information, see What are gene families? in the Handbook.
How are changes in the FOXG1 gene related to health conditions?
Where is the FOXG1 gene located?
Cytogenetic Location: 14q13
Molecular Location on chromosome 14: base pairs 29,236,277 to 29,239,482
The FOXG1 gene is located on the long (q) arm of chromosome 14 at position 13.
More precisely, the FOXG1 gene is located from base pair 29,236,277 to base pair 29,239,482 on chromosome 14.
See How do geneticists indicate the location of a gene? in the Handbook.
Where can I find additional information about FOXG1?
You and your healthcare professional may find the following resources about FOXG1 helpful.
You may also be interested in these resources, which are designed for genetics professionals and researchers.
What other names do people use for the FOXG1 gene or gene products?
See How are genetic conditions and genes named? in the Handbook.
Where can I find general information about genes?
The Handbook provides basic information about genetics in clear language.
These links provide additional genetics resources that may be useful.
What glossary definitions help with understanding FOXG1?
You may find definitions for these and many other terms in the Genetics Home Reference Glossary.
See also Understanding Medical Terminology.
References (9 links)
The resources on this site should not be used as a substitute for professional medical care or advice. Users seeking information about a personal genetic disease, syndrome, or condition should consult with a qualified healthcare professional. See How can I find a genetics professional in my area? in the Handbook.