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Reviewed July 2011
What is the official name of the MCEE gene?
The official name of this gene is “methylmalonyl CoA epimerase.”
MCEE is the gene's official symbol. The MCEE gene is also known by other names, listed below.
Read more about gene names and symbols on the About page.
What is the normal function of the MCEE gene?
The MCEE gene provides instructions for making an enzyme called methylmalonyl CoA epimerase, which converts one form of the molecule methylmalonyl CoA to another. Specifically, the enzyme converts D-methylmalonyl CoA to L-methylmalonyl CoA. This conversion takes place within the pathway that converts the molecule propionyl-CoA to succinyl-CoA. This pathway is important in the breakdown of certain protein building blocks (amino acids), specific fats (lipids), and cholesterol.
How are changes in the MCEE gene related to health conditions?
Where is the MCEE gene located?
Cytogenetic Location: 2p13.3
Molecular Location on chromosome 2: base pairs 71,109,675 to 71,130,263
The MCEE gene is located on the short (p) arm of chromosome 2 at position 13.3.
More precisely, the MCEE gene is located from base pair 71,109,675 to base pair 71,130,263 on chromosome 2.
See How do geneticists indicate the location of a gene? in the Handbook.
Where can I find additional information about MCEE?
You and your healthcare professional may find the following resources about MCEE helpful.
You may also be interested in these resources, which are designed for genetics professionals and researchers.
What other names do people use for the MCEE gene or gene products?
See How are genetic conditions and genes named? in the Handbook.
Where can I find general information about genes?
The Handbook provides basic information about genetics in clear language.
These links provide additional genetics resources that may be useful.
What glossary definitions help with understanding MCEE?
You may find definitions for these and many other terms in the Genetics Home Reference Glossary.
See also Understanding Medical Terminology.
References (5 links)
The resources on this site should not be used as a substitute for professional medical care or advice. Users seeking information about a personal genetic disease, syndrome, or condition should consult with a qualified healthcare professional. See How can I find a genetics professional in my area? in the Handbook.