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Reviewed March 2014
What is the official name of the MOCS1 gene?
The official name of this gene is “molybdenum cofactor synthesis 1.”
MOCS1 is the gene's official symbol. The MOCS1 gene is also known by other names, listed below.
Read more about gene names and symbols on the About page.
What is the normal function of the MOCS1 gene?
The MOCS1 gene provides instructions for making two different proteins, MOCS1A and MOCS1B. Both are involved in the formation (biosynthesis) of a molecule called molybdenum cofactor. Specifically, MOCS1A and MOCS1B perform the first of a series of reactions that produce the cofactor, although the function of MOCS1B in this process is not understood. Molybdenum cofactor, which contains the element molybdenum, is essential to the function of several enzymes called sulfite oxidase, aldehyde oxidase, xanthine dehydrogenase, and mitochondrial amidoxime reducing component (mARC). These enzymes help break down (metabolize) different substances in the body, some of which are toxic if not metabolized.
How are changes in the MOCS1 gene related to health conditions?
Where is the MOCS1 gene located?
Cytogenetic Location: 6p21.3
Molecular Location on chromosome 6: base pairs 39,904,257 to 39,934,550
The MOCS1 gene is located on the short (p) arm of chromosome 6 at position 21.3.
More precisely, the MOCS1 gene is located from base pair 39,904,257 to base pair 39,934,550 on chromosome 6.
See How do geneticists indicate the location of a gene? in the Handbook.
Where can I find additional information about MOCS1?
You and your healthcare professional may find the following resources about MOCS1 helpful.
You may also be interested in these resources, which are designed for genetics professionals and researchers.
What other names do people use for the MOCS1 gene or gene products?
See How are genetic conditions and genes named? in the Handbook.
Where can I find general information about genes?
The Handbook provides basic information about genetics in clear language.
These links provide additional genetics resources that may be useful.
What glossary definitions help with understanding MOCS1?
You may find definitions for these and many other terms in the Genetics Home Reference Glossary.
See also Understanding Medical Terminology.
References (5 links)
The resources on this site should not be used as a substitute for professional medical care or advice. Users seeking information about a personal genetic disease, syndrome, or condition should consult with a qualified healthcare professional. See How can I find a genetics professional in my area? in the Handbook.