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Reviewed January 2010
What is the official name of the MTMR2 gene?
The official name of this gene is “myotubularin related protein 2.”
MTMR2 is the gene's official symbol. The MTMR2 gene is also known by other names, listed below.
Read more about gene names and symbols on the About page.
What is the normal function of the MTMR2 gene?
The MTMR2 gene provides instructions for making an enzyme called myotubularin related protein 2. This enzyme is a phosphatase, which means it helps remove a phosphate group (a cluster of one phosphorus atom and three oxygen atoms) from other substances. Removal of a phosphate group modifies the activity of these substances.
The MTMR2 protein modifies substances that act as chemical messengers. These messengers relay signals from receptors on the cell surface to specific compartments inside the cell, through a process called signal transduction. Signal transduction helps cells respond to their environment, for example, by dividing or maturing to take on specialized functions. The MTMR2 protein modifies chemical messengers that help regulate processes such as the transport of fats (lipids) and proteins within the cell.
Does the MTMR2 gene share characteristics with other genes?
The MTMR2 gene belongs to a family of genes called PTP (protein tyrosine phosphatases).
A gene family is a group of genes that share important characteristics. Classifying individual genes into families helps researchers describe how genes are related to each other. For more information, see What are gene families? in the Handbook.
How are changes in the MTMR2 gene related to health conditions?
Where is the MTMR2 gene located?
Cytogenetic Location: 11q22
Molecular Location on chromosome 11: base pairs 95,566,043 to 95,657,370
The MTMR2 gene is located on the long (q) arm of chromosome 11 at position 22.
More precisely, the MTMR2 gene is located from base pair 95,566,043 to base pair 95,657,370 on chromosome 11.
See How do geneticists indicate the location of a gene? in the Handbook.
Where can I find additional information about MTMR2?
You and your healthcare professional may find the following resources about MTMR2 helpful.
You may also be interested in these resources, which are designed for genetics professionals and researchers.
What other names do people use for the MTMR2 gene or gene products?
See How are genetic conditions and genes named? in the Handbook.
Where can I find general information about genes?
The Handbook provides basic information about genetics in clear language.
These links provide additional genetics resources that may be useful.
What glossary definitions help with understanding MTMR2?
You may find definitions for these and many other terms in the Genetics Home Reference Glossary.
See also Understanding Medical Terminology.
References (9 links)
The resources on this site should not be used as a substitute for professional medical care or advice. Users seeking information about a personal genetic disease, syndrome, or condition should consult with a qualified healthcare professional. See How can I find a genetics professional in my area? in the Handbook.