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The official name of this gene is “neurofilament, medium polypeptide.”
NEFM is the gene's official symbol. The NEFM gene is also known by other names, listed below.
The NEFM gene provides the instructions to make the medium component (subunit) of neurofilaments. Neurofilaments, which are assembled from light, medium, and heavy subunits, are essential for normal nerve function. They form a structural framework that helps to define the shape and size of nerve cells. Cross-linking or bridging between neurofilaments maintains the diameter of the fiber, or axon, that extends from a nerve cell. Maintaining the proper axon diameter is essential for the conduction of nerve impulses.
Cytogenetic Location: 8p21
Molecular Location on chromosome 8: base pairs 24,771,273 to 24,776,605
The NEFM gene is located on the short (p) arm of chromosome 8 at position 21.
More precisely, the NEFM gene is located from base pair 24,771,273 to base pair 24,776,605 on chromosome 8.
See How do geneticists indicate the location of a gene? (http://ghr.nlm.nih.gov/handbook/howgeneswork/genelocation) in the Handbook.
You may also be interested in these resources, which are designed for genetics professionals and researchers.
See How are genetic conditions and genes named? (http://ghr.nlm.nih.gov/handbook/mutationsanddisorders/naming) in the Handbook.
cell ; diameter ; gene ; nerve cell ; neurofilament ; protein ; subunit
You may find definitions for these and many other terms in the Genetics Home Reference Glossary (http://www.ghr.nlm.nih.gov/glossary).
The resources on this site should not be used as a substitute for professional medical care or advice. Users seeking information about a personal genetic disease, syndrome, or condition should consult with a qualified healthcare professional. See How can I find a genetics professional in my area? (http://ghr.nlm.nih.gov/handbook/consult/findingprofessional) in the Handbook.