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Reviewed December 2011
What is the official name of the OXCT1 gene?
The official name of this gene is “3-oxoacid CoA transferase 1.”
OXCT1 is the gene's official symbol. The OXCT1 gene is also known by other names, listed below.
Read more about gene names and symbols on the About page.
What is the normal function of the OXCT1 gene?
The OXCT1 gene provides instruction for making an enzyme called succinyl-CoA:3-ketoacid CoA transferase, often abbreviated as SCOT. The SCOT enzyme is made in the energy-producing centers of cells (mitochondria). The enzyme plays a role in the breakdown of ketones, which are molecules produced by the liver during the breakdown of fats. Ketones are an important source of energy during prolonged periods without food (fasting) or when energy demands are increased, such as during illness or when exercising. In the processing of ketones, the SCOT enzyme converts the molecule acetoacetate to acetoacetyl-CoA.
How are changes in the OXCT1 gene related to health conditions?
Where is the OXCT1 gene located?
Cytogenetic Location: 5p13.1
Molecular Location on chromosome 5: base pairs 41,730,166 to 41,870,790
The OXCT1 gene is located on the short (p) arm of chromosome 5 at position 13.1.
More precisely, the OXCT1 gene is located from base pair 41,730,166 to base pair 41,870,790 on chromosome 5.
See How do geneticists indicate the location of a gene? in the Handbook.
Where can I find additional information about OXCT1?
You and your healthcare professional may find the following resources about OXCT1 helpful.
You may also be interested in these resources, which are designed for genetics professionals and researchers.
What other names do people use for the OXCT1 gene or gene products?
See How are genetic conditions and genes named? in the Handbook.
Where can I find general information about genes?
The Handbook provides basic information about genetics in clear language.
These links provide additional genetics resources that may be useful.
What glossary definitions help with understanding OXCT1?
You may find definitions for these and many other terms in the Genetics Home Reference Glossary.
See also Understanding Medical Terminology.
References (7 links)
The resources on this site should not be used as a substitute for professional medical care or advice. Users seeking information about a personal genetic disease, syndrome, or condition should consult with a qualified healthcare professional. See How can I find a genetics professional in my area? in the Handbook.