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Reviewed October 2006
What is the official name of the PANK2 gene?
The official name of this gene is “pantothenate kinase 2.”
PANK2 is the gene's official symbol. The PANK2 gene is also known by other names, listed below.
Read more about gene names and symbols on the About page.
What is the normal function of the PANK2 gene?
The PANK2 gene provides instructions for making an enzyme called pantothenate kinase 2. This enzyme is active in specialized cellular structures called mitochondria, which are the cell's energy-producing centers. Within mitochondria, pantothenate kinase 2 regulates the formation of a molecule called coenzyme A. Coenzyme A is found in all living cells, where it is essential for the body's production of energy from carbohydrates, fats, and some protein building blocks (amino acids).
PANK2 is one of four human genes that provide instructions for making versions of pantothenate kinase. The functions of these different versions probably vary among tissue types and parts of the cell. The version produced by the PANK2 gene is active in cells throughout the body, including nerve cells in the brain.
How are changes in the PANK2 gene related to health conditions?
Where is the PANK2 gene located?
Cytogenetic Location: 20p13
Molecular Location on chromosome 20: base pairs 3,869,485 to 3,904,501
The PANK2 gene is located on the short (p) arm of chromosome 20 at position 13.
More precisely, the PANK2 gene is located from base pair 3,869,485 to base pair 3,904,501 on chromosome 20.
See How do geneticists indicate the location of a gene? in the Handbook.
Where can I find additional information about PANK2?
You and your healthcare professional may find the following resources about PANK2 helpful.
You may also be interested in these resources, which are designed for genetics professionals and researchers.
What other names do people use for the PANK2 gene or gene products?
See How are genetic conditions and genes named? in the Handbook.
Where can I find general information about genes?
The Handbook provides basic information about genetics in clear language.
These links provide additional genetics resources that may be useful.
What glossary definitions help with understanding PANK2?
You may find definitions for these and many other terms in the Genetics Home Reference Glossary.
See also Understanding Medical Terminology.
References (11 links)
The resources on this site should not be used as a substitute for professional medical care or advice. Users seeking information about a personal genetic disease, syndrome, or condition should consult with a qualified healthcare professional. See How can I find a genetics professional in my area? in the Handbook.