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Reviewed February 2008
What is the official name of the SLC2A1 gene?
The official name of this gene is “solute carrier family 2 (facilitated glucose transporter), member 1.”
SLC2A1 is the gene's official symbol. The SLC2A1 gene is also known by other names, listed below.
Read more about gene names and symbols on the About page.
What is the normal function of the SLC2A1 gene?
The SLC2A1 gene provides instructions for producing a protein called the glucose transporter protein type 1 (GLUT1). This protein is part of the membranes of cells, where it transports glucose (a simple sugar) from the blood into the cells for use as fuel.
Glucose transporter protein type 1 is involved in moving glucose across the blood-brain barrier, which is the boundary that separates tiny blood vessels (capillaries) from the surrounding brain tissue. Glucose is the brain's main energy source under normal conditions. The blood-brain barrier protects the brain's delicate nerve tissue by preventing many other types of molecules from entering the brain.
Does the SLC2A1 gene share characteristics with other genes?
The SLC2A1 gene belongs to a family of genes called SLC (solute carriers).
A gene family is a group of genes that share important characteristics. Classifying individual genes into families helps researchers describe how genes are related to each other. For more information, see What are gene families? in the Handbook.
How are changes in the SLC2A1 gene related to health conditions?
Where is the SLC2A1 gene located?
Cytogenetic Location: 1p34.2
Molecular Location on chromosome 1: base pairs 43,391,045 to 43,424,846
The SLC2A1 gene is located on the short (p) arm of chromosome 1 at position 34.2.
More precisely, the SLC2A1 gene is located from base pair 43,391,045 to base pair 43,424,846 on chromosome 1.
See How do geneticists indicate the location of a gene? in the Handbook.
Where can I find additional information about SLC2A1?
You and your healthcare professional may find the following resources about SLC2A1 helpful.
You may also be interested in these resources, which are designed for genetics professionals and researchers.
What other names do people use for the SLC2A1 gene or gene products?
See How are genetic conditions and genes named? in the Handbook.
Where can I find general information about genes?
The Handbook provides basic information about genetics in clear language.
These links provide additional genetics resources that may be useful.
What glossary definitions help with understanding SLC2A1?
You may find definitions for these and many other terms in the Genetics Home Reference Glossary.
See also Understanding Medical Terminology.
References (12 links)
The resources on this site should not be used as a substitute for professional medical care or advice. Users seeking information about a personal genetic disease, syndrome, or condition should consult with a qualified healthcare professional. See How can I find a genetics professional in my area? in the Handbook.