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Reviewed November 2007
What is the official name of the TAZ gene?
The official name of this gene is “tafazzin.”
TAZ is the gene's official symbol. The TAZ gene is also known by other names, listed below.
Read more about gene names and symbols on the About page.
What is the normal function of the TAZ gene?
The TAZ gene provides instructions for producing a group of proteins called tafazzins. Tafazzins seem to have two distinct functions in cells and tissues. First, tafazzins play a role in the maintenance of the inner membrane of energy-producing centers in cells (mitochondria). Specifically, these proteins are involved in maintaining levels of a specific type of fat (lipid) called cardiolipin, which is essential for energy production in the mitochondria. Tafazzins also promote the differentiation and maturation of cells that build bones (osteoblasts), while preventing cells that store fat (adipocytes) from maturing.
How are changes in the TAZ gene related to health conditions?
Where is the TAZ gene located?
Cytogenetic Location: Xq28
Molecular Location on the X chromosome: base pairs 153,639,876 to 153,650,064
The TAZ gene is located on the long (q) arm of the X chromosome at position 28.
More precisely, the TAZ gene is located from base pair 153,639,876 to base pair 153,650,064 on the X chromosome.
See How do geneticists indicate the location of a gene? in the Handbook.
Where can I find additional information about TAZ?
You and your healthcare professional may find the following resources about TAZ helpful.
You may also be interested in these resources, which are designed for genetics professionals and researchers.
What other names do people use for the TAZ gene or gene products?
See How are genetic conditions and genes named? in the Handbook.
Where can I find general information about genes?
The Handbook provides basic information about genetics in clear language.
These links provide additional genetics resources that may be useful.
What glossary definitions help with understanding TAZ?
You may find definitions for these and many other terms in the Genetics Home Reference Glossary.
See also Understanding Medical Terminology.
References (10 links)
The resources on this site should not be used as a substitute for professional medical care or advice. Users seeking information about a personal genetic disease, syndrome, or condition should consult with a qualified healthcare professional. See How can I find a genetics professional in my area? in the Handbook.