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References

These sources were used to develop the Genetics Home Reference gene summary on the WNT3 gene.

Barrow JR, Howell WD, Rule M, Hayashi S, Thomas KR, Capecchi MR, McMahon AP. Wnt3 signaling in the epiblast is required for proper orientation of the anteroposterior axis. Dev Biol. 2007 Dec 1;312(1):312-20. Epub 2007 Sep 26. PubMed citation
Barrow JR, Thomas KR, Boussadia-Zahui O, Moore R, Kemler R, Capecchi MR, McMahon AP. Ectodermal Wnt3/beta-catenin signaling is required for the establishment and maintenance of the apical ectodermal ridge. Genes Dev. 2003 Feb 1;17(3):394-409. PubMed citation
Entrez Gene
Gene Review: Tetra-Amelia Syndrome
Katoh M. Molecular cloning and characterization of human WNT3. Int J Oncol. 2001 Nov;19(5):977-82. PubMed citation
Liu P, Wakamiya M, Shea MJ, Albrecht U, Behringer RR, Bradley A. Requirement for Wnt3 in vertebrate axis formation. Nat Genet. 1999 Aug;22(4):361-5. PubMed citation
Niemann S, Zhao C, Pascu F, Stahl U, Aulepp U, Niswander L, Weber JL, Müller U. Homozygous WNT3 mutation causes tetra-amelia in a large consanguineous family. Am J Hum Genet. 2004 Mar;74(3):558-63. Epub 2004 Feb 5. PubMed citation
Roelink H, Wang J, Black DM, Solomon E, Nusse R. Molecular cloning and chromosomal localization to 17q21 of the human WNT3 gene. Genomics. 1993 Sep;17(3):790-2. PubMed citation

Reviewed: February 2008

Published: June 10, 2013