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Reviewed July 2013
What is the official name of the ZMYM2 gene?
The official name of this gene is “zinc finger, MYM-type 2.”
ZMYM2 is the gene's official symbol. The ZMYM2 gene is also known by other names, listed below.
Read more about gene names and symbols on the About page.
What is the normal function of the ZMYM2 gene?
The ZMYM2 gene (previously known as ZNF198) provides instructions for making a protein whose function is not clearly understood. It is a member of a family of zinc finger proteins, which contain one or more short regions called zinc finger domains. The zinc finger domains in the ZMYM2 protein are thought to allow it to regulate interactions between other proteins. ZMYM2 is found in the nucleus of the cell, where it likely associates with other proteins. Through these associations, the ZMYM2 protein may be involved in repairing DNA mistakes, controlling gene activity, or forming structures in the nucleus called PML nuclear bodies that block the growth and division of cells and promote their self-destruction (apoptosis).
Does the ZMYM2 gene share characteristics with other genes?
The ZMYM2 gene belongs to a family of genes called ZMYM (zinc fingers, MYM type).
A gene family is a group of genes that share important characteristics. Classifying individual genes into families helps researchers describe how genes are related to each other. For more information, see What are gene families? in the Handbook.
How are changes in the ZMYM2 gene related to health conditions?
Where is the ZMYM2 gene located?
Cytogenetic Location: 13q11-q12
Molecular Location on chromosome 13: base pairs 19,957,567 to 20,091,828
The ZMYM2 gene is located on the long (q) arm of chromosome 13 between positions 11 and 12.
More precisely, the ZMYM2 gene is located from base pair 19,957,567 to base pair 20,091,828 on chromosome 13.
See How do geneticists indicate the location of a gene? in the Handbook.
Where can I find additional information about ZMYM2?
You and your healthcare professional may find the following resources about ZMYM2 helpful.
You may also be interested in these resources, which are designed for genetics professionals and researchers.
What other names do people use for the ZMYM2 gene or gene products?
See How are genetic conditions and genes named? in the Handbook.
Where can I find general information about genes?
The Handbook provides basic information about genetics in clear language.
These links provide additional genetics resources that may be useful.
What glossary definitions help with understanding ZMYM2?
acute ; acute myeloid leukemia ; apoptosis ; atypical ; cancer ; cell ; chromosome ; DNA ; gene ; leukemia ; lymph ; lymphoma ; myeloid ; nucleus ; protein ; rearrangement ; syndrome ; translocation ; tumor ; white blood cells
You may find definitions for these and many other terms in the Genetics Home Reference Glossary.
See also Understanding Medical Terminology.
References (8 links)
The resources on this site should not be used as a substitute for professional medical care or advice. Users seeking information about a personal genetic disease, syndrome, or condition should consult with a qualified healthcare professional. See How can I find a genetics professional in my area? in the Handbook.