ARHGEF gene family

These sources were used to develop the Genetics Home Reference summary for the ARHGEF gene family.

• Schmidt A, Hall A. Guanine nucleotide exchange factors for Rho GTPases: turning on the switch. Genes Dev. 2002 Jul 1;16(13):1587-609. Review. PubMed citation
• Aittaleb M, Boguth CA, Tesmer JJ. Structure and function of heterotrimeric G protein-regulated Rho guanine nucleotide exchange factors. Mol Pharmacol. 2010 Feb;77(2):111-25. doi: 10.1124/mol.109.061234. Epub 2009 Oct 30. Review. PubMed citation
• Mulinari S, Häcker U. Rho-guanine nucleotide exchange factors during development: Force is nothing without control. Small GTPases. 2010 Jul;1(1):28-43. PubMed citation
• Rossman KL, Der CJ, Sondek J. GEF means go: turning on RHO GTPases with guanine nucleotide-exchange factors. Nat Rev Mol Cell Biol. 2005 Feb;6(2):167-80. Review. PubMed citation