A service of the
U.S. National Library of Medicine®
ARHGEF gene family
These sources were used to develop the Genetics Home Reference summary for the ARHGEF gene family.
Schmidt A, Hall A. Guanine nucleotide exchange factors for Rho GTPases: turning on the switch. Genes Dev. 2002 Jul 1;16(13):1587-609. Review.
Aittaleb M, Boguth CA, Tesmer JJ. Structure and function of heterotrimeric G protein-regulated Rho guanine nucleotide exchange factors. Mol Pharmacol. 2010 Feb;77(2):111-25. doi: 10.1124/mol.109.061234. Epub 2009 Oct 30. Review.
Mulinari S, Häcker U. Rho-guanine nucleotide exchange factors during development: Force is nothing without control. Small GTPases. 2010 Jul;1(1):28-43.
Rossman KL, Der CJ, Sondek J. GEF means go: turning on RHO GTPases with guanine nucleotide-exchange factors. Nat Rev Mol Cell Biol. 2005 Feb;6(2):167-80. Review.
Reviewed: August 2012
Published: June 10, 2013
Lister Hill National Center for Biomedical
U.S. National Library of
National Institutes of
Department of Health & Human
Freedom of Information
Indicates a page outside Genetics Home Reference.
Links to web sites outside the Federal Government do not constitute an endorsement.
Selection Criteria for Web Links
This site complies with the
for trustworthy health information: