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Glycosyltransferase group 1 domain containing

Glycosyltransferase group 1 domain containing gene family

Reviewed April 2014

What are the glycosyltransferase group 1 domain containing genes?

Genes in this family provide instructions for making enzymes that act as glycosyltransferases. Glycosyltransferases modify molecules including proteins, sugars, and fats (lipids) by adding single or multiple sugar molecules to them through a process called glycosylation. Each sugar is transferred from one molecule, called the donor, to another molecule, called the acceptor; the donor and acceptor molecules are often proteins or lipids. Glycosylation modifies the acceptor molecules so they can perform a wider variety of functions. It often takes multiple glycosyltransferases to complete the process of glycosylation on a single protein or lipid.

Mutations in genes in the glycosyltransferase group 1 domain containing gene family disrupt the normal glycosylation of proteins and lipids and impair their function. Because glycosylation is performed on a variety of proteins and lipids that are involved in many functions throughout the body, changes in glycosyltransferase genes can cause a range of disorders that affect different body systems.

Which genes are included in the glycosyltransferase group 1 domain containing gene family?

The HUGO Gene Nomenclature Committee (HGNC) provides a list of genes in the glycosyltransferase group 1 domain containing familyThis link leads to a site outside Genetics Home Reference..

Genetics Home Reference summarizes the normal function and health implications of these members of the glycosyltransferase group 1 domain containing gene family: GYS1, GYS2, and PIGA.

What conditions are related to genes in the glycosyltransferase group 1 domain containing gene family?

Genetics Home Reference includes these conditions related to genes in the glycosyltransferase group 1 domain containing gene family:

Where can I find additional information about the glycosyltransferase group 1 domain containing gene family?

You may find the following resources about the glycosyltransferase group 1 domain containing gene family helpful.

Where can I find general information about genes and gene families?

The Handbook provides basic information about genetics in clear language.

What glossary definitions help with understanding the glycosyltransferase group 1 domain containing gene family?

class ; domain ; gene ; glycan ; glycogen ; glycosylation ; lipid ; molecule ; protein

You may find definitions for these and many other terms in the Genetics Home Reference Glossary.

See also Understanding Medical Terminology.

References (3 links)

 

The resources on this site should not be used as a substitute for professional medical care or advice. Users seeking information about a personal genetic disease, syndrome, or condition should consult with a qualified healthcare professional. See How can I find a genetics professional in my area? in the Handbook.

 
Reviewed: April 2014
Published: September 15, 2014