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Apolipoprotein A-I

Synonym(s)

  • Apo A1
  • Apo A-1
  • Apo AI
  • Apo A-I

Definition(s)

The major protein component of high density lipoproteins. It is instrumental in promoting efflux of cholesterol from extrahepatic tissue to the liver where it is metabolized and excreted from the body. The compound is the activator of lecithin-cholesterol acyltransferase which forms cholesteryl esters in HDL. The gene for this apolipoprotein is found on the long arm of chromosome 11.

Definition from: MeSH via Unified Medical Language SystemThis link leads to a site outside Genetics Home Reference. at the National Library of Medicine

See also Understanding Medical Terminology.

 
Published: July 7, 2014