Definition(s)
- A gene on one of the non-sex chromosomes that is always expressed, even if only one copy is present.
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Definition from: Human Genome Project Information
at the U.S. Department of Energy
- Describes
a trait or disorder in which the phenotype is expressed in those who have
inherited only one copy of a particular gene mutation (heterozygotes); specifically
refers to a gene on one of the 22 pairs of autosomes (non-sex chromosomes)
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Definition from: GeneReviews
from the University of Washington and the National Center for Biotechnology Information
- Autosomal dominance is a pattern of inheritance characteristic of some genetic diseases. "Autosomal" means that the gene in question is located on one of the numbered, or non-sex, chromosomes. "Dominant" means that a single copy of the disease-associated mutation is enough to cause the disease. This is in contrast to a recessive disorder, where two copies of the mutation are needed to cause the disease. Huntington's disease is a common example of an autosomal dominant genetic disorder.
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Definition from: Talking Glossary of Genetic Terms from the National Human Genome Research Institute
Related discussion in the Handbook
See also Understanding Medical Terminology.
