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Centromere

Synonym(s)

  • kinetochore

Definition(s)

The clear constricted portion of the chromosome at which the chromatids are joined and by which the chromosome is attached to the spindle during cell division.

Definition from: MeSH via Unified Medical Language SystemThis link leads to a site outside Genetics Home Reference. at the National Library of Medicine

The point or region on a chromosome to which the spindle attaches during mitosis and meiosis -- called also kinetochore.

Definition from: Merriam-Webster's Medical DictionaryThis link leads to a site outside Genetics Home Reference. by Merriam-Webster Inc.

A centromere is a constricted region of a chromosome that separates it into a short arm (p) and a long arm (q). During cell division, the chromosomes first replicate so that each daughter cell receives a complete set of chromosomes. Following DNA replication, the chromosome consists of two identical structures called sister chromatids, which are joined at the centromere.

Definition from: Talking Glossary of Genetic TermsThis link leads to a site outside Genetics Home Reference. from the National Human Genome Research Institute

Related discussion in the Handbook

See also Understanding Medical Terminology.

 
Published: December 22, 2014