Skip Navigation
Genetics Home Reference: your guide to understanding genetic conditions About   Site Map   Contact Us
 
Home A service of the U.S. National Library of Medicine®
A | B | C | D | E | F | G | H | I | J | K | L | M | N | O | P | Q-R | S | T | U | V | W | X | Y-Z

Genetic recombination

Synonym(s)

  • crossing over
  • DNA recombination
  • recombination, genetic

Definition(s)

The exchange of a segment of DNA between two homologous chromosomes during meiosis leading to a novel combination of genetic material in the offspring.

Definition from: GeneReviewsThis link leads to a site outside Genetics Home Reference. from the University of Washington and the National Center for Biotechnology Information

Crossing over is the swapping of genetic material that occurs in the germ line. During the formation of egg and sperm cells, also known as meiosis, paired chromosomes from each parent align so that similar DNA sequences from the paired chromosomes cross over one another. Crossing over results in a shuffling of genetic material and is an important cause of the genetic variation seen among offspring.

Definition from: Talking Glossary of Genetic TermsThis link leads to a site outside Genetics Home Reference. from the National Human Genome Research Institute

See also Understanding Medical Terminology.

 
Published: April 17, 2014