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Hotspot mutation region

Definition(s)

DNA sequences of high susceptibility to mutation due to some inherent instability, tendency toward unequal crossing over, or chemical predisposition to single nucleotide substitutions; region where mutations are observed with greater frequency

Definition from: GeneReviewsThis link leads to a site outside Genetics Home Reference. from the University of Washington and the National Center for Biotechnology Information

See also Understanding Medical Terminology.

 
Published: July 28, 2014