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Linkage analysis

Synonym(s)

  • indirect DNA analysis

Definition(s)

The use of several DNA sequence polymorphisms (normal variants) that are near or within a gene of interest to track within a family the inheritance of a disease-causing mutation in that gene

Click here for More information from GeneTestsThis link leads to a site outside Genetics Home Reference.

Definition from: GeneTestsThis link leads to a site outside Genetics Home Reference. from the University of Washington and Children's Health System, Seattle

A gene-hunting technique that traces patterns of heredity in large, high-risk families, in an attempt to locate a disease-causing gene mutation by identifying traits that are co-inherited with it.

Definition from: Office of Rare DiseasesThis link leads to a site outside Genetics Home Reference. at the National Institutes of Health

See also Understanding Medical Terminology.

 
Published: November 20, 2009