Synonym(s)
- metallopeptidases
- metalloproteinases
Definition(s)
- Proteases which use a metal, normally zinc, in the catalytic mechanism. This group of enzymes is inactivated by metal chelators.
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Definition from: MeSH via Unified Medical Language System
at the National Library of Medicine
- Encoded by metalloproteinase genes, metalloproteinases (endopeptidases) use a metal ion, normally zinc, in the catalytic process and preferentially cleave the Gln-Gly peptide bond. Metalloproteinases inactivated by metal chelators.
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Definition from: NCI Thesaurus via Unified Medical Language System
at the National Library of Medicine
See also Understanding Medical Terminology.