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Microsatellite

Synonym(s)

  • short tandem repeats (STRs)

Definition(s)

Repetitive segments of DNA two to five nucleotides in length (dinucleotide/trinucleotide/tetranucleotide repeats), scattered throughout the genome in the non-coding regions between genes or within genes (introns), often used as markers for linkage analysis because of high variability in repeat number between individuals. These regions are inherently unstable and susceptible to mutations.

Definition from: GeneReviewsThis link leads to a site outside Genetics Home Reference. from the University of Washington and the National Center for Biotechnology Information

Microsatellite sequences are repetitive DNA sequences usually several base pairs in length. Microsatellite sequences are composed of non-coding DNA and are not parts of genes. They are used as genetic markers to follow the inheritance of genes in families.

Definition from: Talking Glossary of Genetic TermsThis link leads to a site outside Genetics Home Reference. from the National Human Genome Research Institute

Any of numerous short segments of DNA that are distributed throughout the genome, that consist of repeated sequences of usually two to five nucleotides, and that are often useful markers in studies of genetic linkage because they tend to vary from one individual to another.

Definition from: Merriam-Webster's Medical DictionaryThis link leads to a site outside Genetics Home Reference. by Merriam-Webster Inc.

See also Understanding Medical Terminology.

 
Published: November 17, 2014