- A disease in which the metabolic products of phenylalanine and tyrosine accumulate, resulting in the deposition of homogentisic acid (a brown-black pigment) in the connective tissue. It occurs in alkaptonuria, but has also been observed in connection with exposure to certain chemicals (e.g., phenol, trinitrophenol, benzene derivatives).
Definition from: MeSH via Unified Medical Language System at the National Library of Medicine
- A condition often associated with alkaptonuria and marked by pigment deposits in cartilages, ligaments, and tendons.
Definition from: Merriam-Webster's Medical Dictionary by Merriam-Webster Inc.
See also Understanding Medical Terminology.