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Predisposing mutation

Synonym(s)

  • susceptibility gene

Definition(s)

A gene mutation that increases an individual's susceptibility or predisposition to a certain disease or disorder. When such a mutation is inherited, development of symptoms is more likely but not certain.

Definition from: GeneReviewsThis link leads to a site outside Genetics Home Reference. from the University of Washington and the National Center for Biotechnology Information

Related discussion in the Handbook

See also Understanding Medical Terminology.

 
Published: November 17, 2014