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Single nucleotide polymorphism

Synonym(s)

  • polymorphism, single nucleotide
  • SNPs

Definition(s)

A single nucleotide variation in a genetic sequence that occurs at appreciable frequency in the population.

Definition from: MeSH via Unified Medical Language SystemThis link leads to a site outside Genetics Home Reference. at the National Library of Medicine

A variant DNA sequence in which the purine or pyrimidine base (as cytosine) of a single nucleotide has been replaced by another such base (as thymine).

Definition from: Merriam-Webster's Medical DictionaryThis link leads to a site outside Genetics Home Reference. by Merriam-Webster Inc.

Single nucleotide polymorphisms (SNPs) are a type of polymorphism involving variation of a single base pair. Scientists are studying how single nucleotide polymorphisms, or SNPs (pronounced "snips"), in the human genome correlate with disease, drug response, and other phenotypes.

Definition from: Talking Glossary of Genetic TermsThis link leads to a site outside Genetics Home Reference. from the National Human Genome Research Institute

Related discussion in the Handbook

See also Understanding Medical Terminology.

 
Published: November 17, 2014