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Sister chromatid exchange

Definition(s)

An exchange of homologous segments of genetic material between the sister chromatids of a chromosome, either between the sister chromatids of a meiotic tetrad or between the sister chromatids of a duplicated somatic chromosome. Its frequency is increased as a result of inordinate chromosomal fragility due to genetic or environmental factors such as ultraviolet or ionizing radiation and other mutagenic agents, and is particularly high in Bloom Syndrome.

Definition from: NCI Thesaurus via Unified Medical Language SystemThis link leads to a site outside Genetics Home Reference. at the National Library of Medicine

See also Understanding Medical Terminology.

 
Published: December 22, 2014