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Stop codon

Definition(s)

A stop codon is a trinucleotide sequence within a messenger RNA (mRNA) molecule that signals a halt to protein synthesis. The genetic code describes the relationship between the sequence of DNA bases (A, C, G, and T) in a gene and the corresponding protein sequence that it encodes. The cell reads the sequence of the gene in groups of three bases. Of the 64 possible combinations of three bases, 61 specify an amino acid, while the remaining three combinations are stop codons.

Definition from: Talking Glossary of Genetic TermsThis link leads to a site outside Genetics Home Reference. from the National Human Genome Research Institute

A genetic codon in messenger RNA that signals the termination of protein synthesis during translation.

Definition from: Merriam-Webster's Medical DictionaryThis link leads to a site outside Genetics Home Reference. by Merriam-Webster Inc.

Related discussion in the Handbook

See also Understanding Medical Terminology.

 
Published: July 28, 2014