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Tumor suppressor gene

Synonym(s)

  • antioncogenes
  • anti-oncogenes
  • emerogenes
  • genes, cancer suppressor
  • genes, onco-suppressor
  • genes, tumor suppressor
  • oncosuppressor gene
  • tumor suppressing genes

Definition(s)

Genes in the body that can suppress or block the development of cancer.

Definition from: Physician Data Query via Unified Medical Language SystemThis link leads to a site outside Genetics Home Reference. at the National Library of Medicine

A tumor suppressor gene directs the production of a protein that is part of the system that regulates cell division. The tumor suppressor protein plays a role in keeping cell division in check. When mutated, a tumor suppressor gene is unable to do its job, and as a result uncontrolled cell growth may occur. This may contribute to the development of a cancer.

Definition from: Talking Glossary of Genetic TermsThis link leads to a site outside Genetics Home Reference. from the National Human Genome Research Institute

See also Understanding Medical Terminology.

 
Published: July 21, 2014